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OrbiMed Portfolio holdings

AUM $5.4B
1-Year Est. Return 163.13%
This Fund
S&P 500
This Quarter Est. Return
-4.57%
1 Year Est. Return
+163.13%
3 Year Est. Return
+393.16%
5 Year Est. Return
+486.34%
10 Year Est. Return
+3,312.73%
AUM
$9.89B
AUM Growth
-$808M
Cap. Flow
+$275M
Cap. Flow %
2.78%
Top 10 Hldgs %
30.49%
Holding
183
New
24
Increased
25
Reduced
25
Closed
24

Sector Composition

Rank Sector Weight
1 Healthcare 95.72%
2 Miscellaneous 4.15%
3 Technology 0.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow
NBIX icon
26
Neurocrine Biosciences
NBIX
$15.7B
$120M 1.21%
1,231,115
-70,600
-5% -$6.77M
XTNT icon
27
Xtant Medical Holdings
XTNT
$53.9M
$119M 1.2%
72,873,494
EW icon
28
Edwards Lifesciences
EW
$52B
$117M 1.18%
1,126,400
RPTX
29
DELISTED
Repare Therapeutics
RPTX
$107M 1.08%
3,426,325
GRCL
30
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$103M 1.04%
7,884,870
NPCE icon
31
Neuropace
NPCE
$495M
$95.5M 0.97%
+4,012,281
New +$93.1M
AFIB
32
DELISTED
Acutus Medical Inc
AFIB
$93M 0.94%
5,477,958
PASG icon
33
Passage Bio
PASG
$14.5M
$92.2M 0.93%
348,145
KNTE
34
DELISTED
Kinnate Biopharma Inc. Common Stock
KNTE
$89.6M 0.91%
3,847,929
SYK icon
35
Stryker
SYK
$127B
$87.6M 0.89%
337,400
JANX icon
36
Janux Therapeutics
JANX
$1.1B
$86.5M 0.87%
+3,466,386
New +$77.2M
IMGN
37
DELISTED
Immunogen Inc
IMGN
$85.3M 0.86%
12,936,622
+3,804,800
+42% +$26.5M
CRSP icon
38
CRISPR Therapeutics
CRSP
$5.58B
$84M 0.85%
519,000
-33,500
-6% -$4.07M
PGNY icon
39
Progyny
PGNY
$1.99B
$80.6M 0.81%
1,365,445
-559,815
-29% -$31.4M
AUPH icon
40
Aurinia Pharmaceuticals
AUPH
$2.17B
$78.7M 0.8%
6,069,032
OSH
41
DELISTED
Oak Street Health, Inc.
OSH
$77.8M 0.79%
1,328,300
+361,300
+37% +$21.5M
SVA
42
DELISTED
Sinovac Biotech, Ltd
SVA
$76.8M 0.78%
2,839,500
ACET icon
43
Adicet Bio
ACET
$84.8M
$74.4M 0.75%
452,054
KROS icon
44
Keros Therapeutics
KROS
$219M
$71.3M 0.72%
1,679,417
ETNB
45
DELISTED
89bio
ETNB
$69.7M 0.71%
3,729,442
TBPH icon
46
Theravance Biopharma
TBPH
$885M
$66.3M 0.67%
4,564,045
-1,655,065
-27% -$31.1M
MGTX icon
47
MeiraGTx Holdings
MGTX
$1.33B
$63.6M 0.64%
4,102,925
VECT
48
DELISTED
VectivBio Holding AG Ordinary Shares
VECT
$59.7M 0.6%
+5,123,304
New +$77.8M
ASND icon
49
Ascendis Pharma A/S
ASND
$16.3B
$58.9M 0.6%
447,859
-57,300
-11% -$7.64M
CRNX icon
50
Crinetics Pharmaceuticals
CRNX
$9B
$56.5M 0.57%
2,996,876
+243,309
+9% +$4.28M

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OrbiMed's Q2 2021 Portfolio in Review

As of Q2 2021, OrbiMed held 183 positions worth $9.89B, down 7.6% from $10.7B the previous quarter. Its ten largest holdings account for 30% of the portfolio.

OrbiMed's Q2 2021 filing shows 24 new, 25 increased, 25 reduced and 24 closed positions. Its largest new stake was State Street SPDR S&P Biotech ETF: 935,700 shares worth $127M. The largest sale was Haemonetics, an estimated $94.6M.

By sector, the portfolio is most concentrated in Healthcare at 96% of assets, up from 96% a quarter earlier, followed by Miscellaneous and Technology.

  • OrbiMed's largest Q2 2021 buy was State Street SPDR S&P Biotech ETF: 935,700 shares worth $127M.
  • OrbiMed added most to Deciphera Pharmaceuticals, Inc. Common Stock in Q2 2021, an estimated $74.2M increase.
  • OrbiMed's biggest Q2 2021 reduction was AbCellera Biologics, cutting an estimated $54.5M.
  • OrbiMed fully exited Haemonetics in Q2 2021, selling an estimated $94.6M.
  • OrbiMed's ten largest holdings make up 30% of its $9.89B portfolio in Q2 2021.
  • OrbiMed opened 24 new positions and closed 24 in Q2 2021.
  • OrbiMed's portfolio value fell 7.6% quarter-over-quarter to $9.89B.

Based on OrbiMed's 13F filing for Q2 2021, filed 16 Aug 2021.