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OrbiMed Portfolio holdings

AUM $5.4B Turnover 40.13%
1-Year Est. Return 163.13%
This Fund
S&P 500
This Quarter Est. Return
-4.57%
1 Year Est. Return
+163.13%
3 Year Est. Return
+393.16%
5 Year Est. Return
+486.34%
10 Year Est. Return
+3,312.73%
AUM
$9.89B
AUM Growth
-$808M
Cap. Flow
+$275M
Cap. Flow %
2.78%
Top 10 Hldgs %
30.49%
Holding
183
New
24
Increased
25
Reduced
25
Closed
24
Avg Time Held Equity + Options
1.7 years
Top 10 Avg Time Held Equity + Options
0.5 years
Top 20 Avg Time Held Equity + Options
1.6 years
Avg Time Held Equity only
1.7 years
Top 10 Avg Time Held Equity only
0.5 years
Top 20 Avg Time Held Equity only
1.6 years

Sector Composition

Rank Sector Weight
1 Healthcare 95.72%
2 Miscellaneous 4.15%
3 Technology 0.13%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
NBIX icon
26
Neurocrine Biosciences
NBIX
$13.8B
$120M 1.21%
1,231,115
-70,600
-5% -$6.77M
2018 Q1
13 quarters
XTNT icon
27
Xtant Medical Holdings
XTNT
$44.7M
$119M 1.2%
72,873,494
– –
2013 Q2
32 quarters
EW icon
28
Edwards Lifesciences
EW
$49.8B
$117M 1.18%
1,126,400
– –
2016 Q1
21 quarters
RPTX icon
29
DELISTED
Repare Therapeutics
RPTX
$107M 1.08%
3,426,325
– –
2020 Q2
4 quarters
GRCL
30
DELISTED
Gracell Biotechnologies Inc. American Depositary Shares
GRCL
$103M 1.04%
7,884,870
– –
2021 Q1
1 quarter
NPCE icon
31
Neuropace
NPCE
$431M
$95.5M 0.97%
+4,012,281
New +$93.1M
2021 Q2
0 quarters
AFIB icon
32
DELISTED
Acutus Medical Inc
AFIB
$93M 0.94%
5,477,958
– –
2020 Q3
3 quarters
PASG icon
33
Passage Bio
PASG
$11.8M
$92.2M 0.93%
348,145
– –
2020 Q1
5 quarters
KNTE
34
DELISTED
Kinnate Biopharma Inc. Common Stock
KNTE
$89.6M 0.91%
3,847,929
– –
2020 Q4
2 quarters
SYK icon
35
Stryker
SYK
$108B
$87.6M 0.89%
337,400
– –
2020 Q3
3 quarters
JANX icon
36
Janux Therapeutics
JANX
$1.05B
$86.5M 0.87%
+3,466,386
New +$77.2M
2021 Q2
0 quarters
IMGN icon
37
DELISTED
Immunogen Inc
IMGN
$85.3M 0.86%
12,936,622
+3,804,800
+42% +$26.5M
2020 Q4
2 quarters
CRSP icon
38
CRISPR Therapeutics
CRSP
$4.86B
$84M 0.85%
519,000
-33,500
-6% -$4.07M
2019 Q3
7 quarters
PGNY icon
39
Progyny
PGNY
$2.14B
$80.6M 0.81%
1,365,445
-559,815
-29% -$31.4M
2020 Q2
4 quarters
AUPH icon
40
Aurinia Pharmaceuticals
AUPH
$2.21B
$78.7M 0.8%
6,069,032
– –
2019 Q1
9 quarters
OSH
41
DELISTED
Oak Street Health, Inc.
OSH
$77.8M 0.79%
1,328,300
+361,300
+37% +$21.5M
2020 Q3
3 quarters
SVA
42
DELISTED
Sinovac Biotech, Ltd
SVA
$76.8M 0.78%
2,839,500
– –
2013 Q2
32 quarters
ACET icon
43
Adicet Bio
ACET
$45.8M
$74.4M 0.75%
452,054
– –
2018 Q1
13 quarters
KROS icon
44
Keros Therapeutics
KROS
$219M
$71.3M 0.72%
1,679,417
– –
2020 Q2
4 quarters
ETNB icon
45
DELISTED
89bio
ETNB
$69.7M 0.71%
3,729,442
– –
2019 Q4
6 quarters
TBPH icon
46
DELISTED
Theravance Biopharma
TBPH
$66.3M 0.67%
4,564,045
-1,655,065
-27% -$31.1M
2020 Q1
5 quarters
MGTX icon
47
MeiraGTx Holdings
MGTX
$904M
$63.6M 0.64%
4,102,925
– –
2018 Q3
11 quarters
VECT
48
DELISTED
VectivBio Holding AG Ordinary Shares
VECT
$59.7M 0.6%
+5,123,304
New +$77.8M
2021 Q2
0 quarters
ASND icon
49
Ascendis Pharma A/S
ASND
$14.9B
$58.9M 0.6%
447,859
-57,300
-11% -$7.64M
2015 Q1
25 quarters
CRNX icon
50
DELISTED
Crinetics Pharmaceuticals
CRNX
$56.5M 0.57%
2,996,876
+243,309
+9% +$4.28M
2018 Q3
11 quarters

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OrbiMed's Q2 2021 Portfolio in Review

As of Q2 2021, OrbiMed held 183 positions worth $9.89B, down 7.6% from $10.7B the previous quarter. Its ten largest holdings account for 30% of the portfolio.

OrbiMed's Q2 2021 filing shows 24 new, 25 increased, 25 reduced and 24 closed positions. Its largest new stake was State Street SPDR S&P Biotech ETF: 935,700 shares worth $127M. The largest sale was Haemonetics, an estimated $94.6M.

By sector, the portfolio is most concentrated in Healthcare at 96% of assets, up from 96% a quarter earlier, followed by Miscellaneous and Technology.

  • OrbiMed's largest Q2 2021 buy was State Street SPDR S&P Biotech ETF: 935,700 shares worth $127M.
  • OrbiMed added most to Deciphera Pharmaceuticals, Inc. Common Stock in Q2 2021, an estimated $74.2M increase.
  • OrbiMed's biggest Q2 2021 reduction was AbCellera Biologics, cutting an estimated $54.5M.
  • OrbiMed fully exited Haemonetics in Q2 2021, selling an estimated $94.6M.
  • OrbiMed's ten largest holdings make up 30% of its $9.89B portfolio in Q2 2021.
  • OrbiMed opened 24 new positions and closed 24 in Q2 2021.
  • OrbiMed's portfolio value fell 7.6% quarter-over-quarter to $9.89B.

Based on OrbiMed's 13F filing for Q2 2021, filed 16 Aug 2021.