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Opaleye Management Portfolio holdings

AUM $1.1B
1-Year Est. Return 197.64%
This Fund
S&P 500
This Quarter Est. Return
+6.78%
1 Year Est. Return
+197.64%
3 Year Est. Return
+748.31%
5 Year Est. Return
+1,163.14%
10 Year Est. Return
+87,953.69%
AUM
$150M
AUM Growth
-$10.7M
Cap. Flow
-$11.4M
Cap. Flow %
-7.61%
Top 10 Hldgs %
46.24%
Holding
65
New
12
Increased
10
Reduced
12
Closed
16
Avg Time Held
3.4 quarters
Top 10 Avg Time Held
2.2 quarters
Top 20 Avg Time Held
3.2 quarters

Sector Composition

Rank Sector Weight
1 Healthcare 91.89%
2 Miscellaneous 8.11%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake
Capital Flow Held Since
NKTR icon
51
Nektar Therapeutics
NKTR
$1.29B
– –
-3,333
Closed -$688K –
PRTA icon
52
Prothena Corp
PRTA
$429M
– –
-14,000
Closed -$576K –
SAGE icon
53
DELISTED
Sage Therapeutics
SAGE
– –
-165,000
Closed -$5.29M –
TVTX icon
54
Travere Therapeutics
TVTX
$4.88B
– –
-150,000
Closed -$2.05M –
XOMA icon
55
DELISTED
Xoma
XOMA
– –
-67,500
Closed -$1.04M –
ALPN icon
56
DELISTED
Alpine Immune Sciences Inc
ALPN
– –
-25,000
Closed -$417K –
NBSE icon
57
DELISTED
NeuBase Therapeutics, Inc. Common Stock
NBSE
– –
-915
Closed -$1.18M –
ISEE
58
DELISTED
IVERIC bio, Inc. Common Stock
ISEE
– –
-80,000
Closed -$3.38M –
CHMA
59
DELISTED
Chiasma, Inc. Common Stock
CHMA
– –
-20,000
Closed -$183K –
AKAO
60
DELISTED
Achaogen Inc
AKAO
– –
-255,000
Closed -$704K –
MDVN
61
DELISTED
MEDIVATION, INC.
MDVN
– –
-14,500
Closed -$667K –

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Opaleye Management's Q2 2016 Portfolio in Review

As of Q2 2016, Opaleye Management held 65 positions worth $150M, down 6.6% from $160M the previous quarter. Its ten largest holdings account for 46% of the portfolio.

Opaleye Management withdrew a net $11.4M in Q2 2016, closing 16 positions and reducing 12 holdings. Its most notable exit was Sage Therapeutics, an estimated $5.29M position sold in full.

By sector, the portfolio is most concentrated in Healthcare at 92% of assets, up from 88% a quarter earlier, followed by Miscellaneous.

Against the trend, Opaleye Management opened a new position in Horizon Therapeutics Public Limited Company Ordinary Shares worth $3.29M.

  • Opaleye Management's largest Q2 2016 buy was Horizon Therapeutics Public Limited Company Ordinary Shares: 200,000 shares worth $3.29M.
  • Opaleye Management added most to Aevi Genomic Medicine Inc in Q2 2016, an estimated $2.06M increase.
  • Opaleye Management's biggest Q2 2016 reduction was Ultragenyx Pharmaceutical, cutting an estimated $2.91M.
  • Opaleye Management fully exited Sage Therapeutics in Q2 2016, selling an estimated $5.29M.
  • Opaleye Management's ten largest holdings make up 46% of its $150M portfolio in Q2 2016.
  • Opaleye Management opened 12 new positions and closed 16 in Q2 2016.
  • Opaleye Management's portfolio value fell 6.6% quarter-over-quarter to $150M.

Based on Opaleye Management's 13F filing for Q2 2016, filed 12 Aug 2016.