OM

Opaleye Management Portfolio holdings

AUM $758M
1-Year Est. Return 77.57%
This Fund
S&P 500
This Quarter Est. Return
1 Year Est. Return
+77.57%
3 Year Est. Return
5 Year Est. Return
10 Year Est. Return
AUM
$758M
AUM Growth
+$50.7M
Cap. Flow
Cap. Flow %
Top 10 Hldgs %
Holding
64
New
Increased
Reduced
Closed

Top Buys

1
+$42.2M
2
+$15M
3
+$12.4M
4
SLGL icon
Sol-Gel Technologies
SLGL
+$9.61M
5
URGN icon
UroGen Pharma
URGN
+$5.82M

Top Sells

1
+$37.3M
2
+$14M
3
+$12.2M
4
SRPT icon
Sarepta Therapeutics
SRPT
+$11.3M
5
LRMR icon
Larimar Therapeutics
LRMR
+$10.6M

Sector Composition

1 Healthcare 100%
Name Market Value Portfolio Weight Shares or Principal Change
in Stake 		Capital Flow
KPTI icon
26
Karyopharm Therapeutics
KPTI
$173M
$6.84M 0.9%
+930,000
JBIO
27
Jade Biosciences
JBIO
$731M
$6.6M 0.87%
+427,608
URGN icon
28
UroGen Pharma
URGN
$1.02B
$6.29M 0.83%
+268,423
ALMS
29
Alumis Inc
ALMS
$3.7B
$5.22M 0.69%
535,000
-130,000
CATX icon
30
Perspective Therapeutics
CATX
$615M
$4.99M 0.66%
+1,184,500
VYGR icon
31
Voyager Therapeutics
VYGR
$228M
$4.7M 0.62%
+1,196,904
RLMD icon
32
Relmada Therapeutics
RLMD
$334M
$4.52M 0.6%
+935,000
TECX
33
Tectonic Therapeutic
TECX
$439M
$4.48M 0.59%
+214,747
PLX icon
34
Protalix BioTherapeutics
PLX
$232M
$4.46M 0.59%
2,478,176
-102,380
TRVI icon
35
Trevi Therapeutics
TRVI
$1.53B
$4.32M 0.57%
345,100
-44,900
FBIO icon
36
Fortress Biotech
FBIO
$106M
$3.99M 0.53%
+1,090,000
RCKT icon
37
Rocket Pharmaceuticals
RCKT
$542M
$3.35M 0.44%
+955,000
MGTX icon
38
MeiraGTx Holdings
MGTX
$609M
$3.11M 0.41%
+390,844
RIGL icon
39
Rigel Pharmaceuticals
RIGL
$631M
$3M 0.4%
70,000
+32,213
ZYME icon
40
Zymeworks
ZYME
$1.76B
$2.87M 0.38%
108,929
+8,929
ASRT icon
41
Assertio
ASRT
$74.8M
$2.58M 0.34%
+285,000
VTYX icon
42
Ventyx Biosciences
VTYX
$1B
$2.27M 0.3%
+251,932
IRD
43
Opus Genetics
IRD
$287M
$2.25M 0.3%
1,120,000
+20,000
STRO icon
44
Sutro Biopharma
STRO
$335M
$2.21M 0.29%
+190,671
CABA icon
45
Cabaletta Bio
CABA
$320M
$1.97M 0.26%
900,000
+91,118
ZNTL icon
46
Zentalis Pharmaceuticals
ZNTL
$155M
$1.89M 0.25%
1,400,906
+1,084,356
GBIO
47
DELISTED
Generation Bio
GBIO
$1.76M 0.23%
+310,000
BBIO icon
48
BridgeBio Pharma
BBIO
$12.9B
$1.4M 0.18%
+18,319
ENTA icon
49
Enanta Pharmaceuticals
ENTA
$415M
$1.18M 0.16%
+75,000
QTTB icon
50
Q32 Bio
QTTB
$56.1M
$708K 0.09%
+213,363
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