Opaleye Management’s Fortress Biotech FBIO Stock Holding History

Opaleye Management’s Portfolio FBIO Stock Details FBIO Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q2	$2.72M	Sell	890,000 -152,000	-15%	-$392K	0.25%	44
2026 Q1	$2.91M	Sell	1,042,000 -48,000	-4%	-$163K	0.38%	42
2025 Q4	$3.99M	Buy	+1,090,000	New	+$3.11M	0.53%	36
2023 Q4	–	Sell	-133,333	Closed	-$581K	–	47
2023 Q3	$581K	Sell	133,333 -87,334	-40%	-$599K	0.19%	38
2023 Q2	$1.82M	Sell	220,667 -84,240	-28%	-$833K	0.44%	37
2023 Q1	$3.75M	Buy	304,907 +168,240	+123%	+$2M	1.12%	30
2022 Q4	$1.34M	Sell	136,667 -63,266	-32%	-$700K	0.47%	36
2022 Q3	$2.58M	Sell	199,933 -16,546	-8%	-$248K	1.07%	24
2022 Q2	$2.73M	Sell	216,479 -33,521	-13%	-$497K	1.23%	23
2022 Q1	$5.1M	Hold	250,000	–	–	1.58%	20
2021 Q4	$9.38M	Hold	250,000	–	–	1.99%	19
2021 Q3	$12.1M	Sell	250,000 -8,333	-3%	-$407K	2.26%	14
2021 Q2	$13.8M	Hold	258,333	–	–	2.3%	14
2021 Q1	$13.7M	Sell	258,333 -834	-0.3%	-$47K	2.01%	14
2020 Q4	$12.3M	Buy	259,167 +3,834	+2%	+$166K	1.61%	18
2020 Q3	$10.3M	Hold	255,333	–	–	2.01%	20
2020 Q2	$10.3M	Buy	+255,333	New	+$9.48M	2.07%	17
2018 Q2	–	Sell	-21,000	Closed	-$1.43M	–	39
2018 Q1	$1.43M	Buy	+21,000	New	+$1.33M	0.41%	33

Other funds holding FBIO

Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM

Mackenzie Financial Toronto Ontario, Ontario, Canada $100B AUM 36.93% 1-Year Est. Return

GCP

GSA Capital Partners London, United Kingdom $1.59B AUM 39.81% 1-Year Est. Return

SAM

Shikiar Asset Management New York $396M AUM 41.06% 1-Year Est. Return

Geode Capital Management Boston, Massachusetts $1.88T AUM 44.46% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Two Sigma Investments New York $138B AUM 41.87% 1-Year Est. Return

BCM

Bridgeway Capital Management Houston, Texas $5.69B AUM 60.64% 1-Year Est. Return

Vanguard Fiduciary Trust Malvern, Pennsylvania $454B AUM

HWM

HB Wealth Management Atlanta, Georgia $17.8B AUM 24.16% 1-Year Est. Return

Opaleye Management's FBIO Position: Q2 2026 in Review

Opaleye Management reduced its Fortress Biotech (FBIO) stake by 15% in Q2 2026, selling an estimated $392K and leaving 890,000 shares worth $2.72M. The position accounts for 0.25% of the portfolio, ranked #44.

Opaleye Management first reported a position in FBIO in Q1 2018 and has held it in 18 quarters since. The position peaked at $13.8M in Q2 2021. 55 funds tracked by Wall St. Rank hold FBIO as of Q2 2026.

Opaleye Management held 890,000 shares of Fortress Biotech worth $2.72M as of Q2 2026.
Opaleye Management sold 152,000 Fortress Biotech shares in Q2 2026, an estimated $392K.
Fortress Biotech made up 0.25% of Opaleye Management's portfolio in Q2 2026, its #44 holding.
Opaleye Management first reported a position in Fortress Biotech in Q1 2018 and has held it in 18 quarters since.
Opaleye Management's Fortress Biotech position peaked at $13.8M in Q2 2021.
55 funds tracked by Wall St. Rank held Fortress Biotech as of Q2 2026.

Based on Opaleye Management's 13F filing for Q2 2026, filed 14 Aug 2026.