Manulife (Manufacturers Life Insurance)’s Xenon Pharmaceuticals XENE Stock Holding History

Manulife (Manufacturers Life Insurance)’s Portfolio XENE Stock Details XENE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$1.26M	Sell	21,684 -10,938	-34%	-$504K	﹤0.01%	1712
2025 Q4	$1.45M	Buy	32,622 +8,690	+36%	+$365K	﹤0.01%	1672
2025 Q3	$961K	Sell	23,932 -2,147	-8%	-$75.6K	﹤0.01%	1872
2025 Q2	$816K	Buy	+26,079	New	+$851K	﹤0.01%	1918

Other funds holding XENE

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

PCH

Polar Capital Holdings London, United Kingdom $28.2B AUM 115.26% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return

Manulife (Manufacturers Life Insurance)'s XENE Position: Q1 2026 in Review

Manulife (Manufacturers Life Insurance) reduced its Xenon Pharmaceuticals (XENE) stake by 34% in Q1 2026, selling an estimated $504K and leaving 21,684 shares worth $1.26M. The position accounts for ﹤0.01% of the portfolio, ranked #1712.

Manulife (Manufacturers Life Insurance) first reported a position in XENE in Q2 2025 and has held it in 4 quarters since. The position peaked at $1.45M in Q4 2025. 290 funds tracked by Wall St. Rank hold XENE as of Q1 2026.

Manulife (Manufacturers Life Insurance) held 21,684 shares of Xenon Pharmaceuticals worth $1.26M as of Q1 2026.
Manulife (Manufacturers Life Insurance) sold 10,938 Xenon Pharmaceuticals shares in Q1 2026, an estimated $504K.
Xenon Pharmaceuticals made up ﹤0.01% of Manulife (Manufacturers Life Insurance)'s portfolio in Q1 2026, its #1712 holding.
Manulife (Manufacturers Life Insurance) first reported a position in Xenon Pharmaceuticals in Q2 2025 and has held it in 4 quarters since.
Manulife (Manufacturers Life Insurance)'s Xenon Pharmaceuticals position peaked at $1.45M in Q4 2025.
290 funds tracked by Wall St. Rank held Xenon Pharmaceuticals as of Q1 2026.

Based on Manulife (Manufacturers Life Insurance)'s 13F filing for Q1 2026, filed 15 May 2026.