Janus Henderson Group
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Janus Henderson Group’s Xenon Pharmaceuticals XENE Stock Holding History

Janus Henderson Group’s Portfolio XENE Stock Details XENE Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$243M Buy
4,175,982
+91,948
+2% +$4.24M 0.12% 174
2025
Q4 		$183M Buy
4,084,034
+140,149
+4% +$5.89M 0.08% 204
2025
Q3 		$158M Buy
3,943,885
+366,150
+10% +$12.9M 0.07% 216
2025
Q2 		$112M Buy
3,577,735
+252,642
+8% +$8.24M 0.05% 250
2025
Q1 		$114M Buy
3,325,093
+458,338
+16% +$17.4M 0.06% 247
2024
Q4 		$112M Buy
2,866,755
+314,363
+12% +$13M 0.06% 263
2024
Q3 		$101M Buy
2,552,392
+1,507,135
+144% +$60.8M 0.05% 279
2024
Q2 		$40.8M Buy
1,045,257
+103,688
+11% +$4.14M 0.02% 425
2024
Q1 		$40.5M Sell
941,569
-24,496
-3% -$1.13M 0.02% 431
2023
Q4 		$44.5M Buy
966,065
+583,760
+153% +$20.6M 0.03% 402
2023
Q3 		$13.1M Buy
382,305
+54,961
+17% +$2.06M 0.01% 612
2023
Q2 		$12.6M Buy
327,344
+5,879
+2% +$234K 0.01% 651
2023
Q1 		$11.5M Buy
321,465
+29,679
+10% +$1.1M 0.01% 683
2022
Q4 		$11.5M Buy
291,786
+57,952
+25% +$2.11M 0.01% 691
2022
Q3 		$8.43M Sell
233,834
-42,840
-15% -$1.54M 0.01% 710
2022
Q2 		$8.41M Buy
276,674
+266,393
+2,591% +$8.06M 0.01% 731
2022
Q1 		$315K Buy
+10,281
New +$308K ﹤0.01% 2188

Other funds holding XENE

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $17.3B AUM 211.34% 1-Year Est. Return
PCH
Polar Capital Holdings London, United Kingdom $42.4B AUM 181.11% 1-Year Est. Return
Capital International Investors
Capital International Investors Los Angeles, California $484B AUM 34.9% 1-Year Est. Return
Citadel Advisors
Citadel Advisors Miami, Florida $875B AUM 40.91% 1-Year Est. Return
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return

Janus Henderson Group's XENE Position: Q1 2026 in Review

Janus Henderson Group increased its Xenon Pharmaceuticals (XENE) stake by 2.3% in Q1 2026, buying an estimated $4.24M and bringing the position to 4,175,982 shares worth $243M. The position accounts for 0.12% of the portfolio, ranked #174.

Janus Henderson Group first reported a position in XENE in Q1 2022 and has held it in 17 quarters since. 290 funds tracked by Wall St. Rank hold XENE as of Q1 2026.

  • Janus Henderson Group held 4,175,982 shares of Xenon Pharmaceuticals worth $243M as of Q1 2026.
  • Janus Henderson Group bought 91,948 Xenon Pharmaceuticals shares in Q1 2026, an estimated $4.24M.
  • Xenon Pharmaceuticals made up 0.12% of Janus Henderson Group's portfolio in Q1 2026, its #174 holding.
  • Janus Henderson Group first reported a position in Xenon Pharmaceuticals in Q1 2022 and has held it in 17 quarters since.
  • 290 funds tracked by Wall St. Rank held Xenon Pharmaceuticals as of Q1 2026.

Based on Janus Henderson Group's 13F filing for Q1 2026, filed 15 May 2026.