Jim Simons’s Opko Health OPK Stock Holding History

Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake
Trade Value Portfolio Weight Portfolio Position
2026
Q1
$125K Buy
+109,543
New +$135K ﹤0.01% 2995
2025
Q4
Sell
-59,700
Closed -$92.5K 3618
2025
Q3
$92.5K Buy
59,700
+21,600
+57% +$29.7K ﹤0.01% 3264
2025
Q2
$50.3K Buy
+38,100
New +$52.1K ﹤0.01% 3392
2025
Q1
Sell
-145,977
Closed -$215K 3735
2024
Q4
$215K Sell
145,977
-312,950
-68% -$478K ﹤0.01% 3148
2024
Q3
$684K Buy
458,927
+174,184
+61% +$259K ﹤0.01% 2644
2024
Q2
$356K Sell
284,743
-1,093,453
-79% -$1.42M ﹤0.01% 2844
2024
Q1
$1.65M Buy
+1,378,196
New +$1.38M ﹤0.01% 2152
2023
Q4
Sell
-808,643
Closed -$1.29M 4018
2023
Q3
$1.29M Buy
808,643
+487,290
+152% +$888K ﹤0.01% 2128
2023
Q2
$697K Sell
321,353
-1,366,790
-81% -$2.14M ﹤0.01% 2698
2023
Q1
$2.46M Sell
1,688,143
-598,400
-26% -$770K ﹤0.01% 1892
2022
Q4
$2.86M Sell
2,286,543
-549,800
-19% -$866K ﹤0.01% 1852
2022
Q3
$5.36M Sell
2,836,343
-1,053,829
-27% -$2.49M 0.01% 1395
2022
Q2
$9.84M Buy
3,890,172
+3,480,129
+849% +$10.1M 0.01% 1125
2022
Q1
$1.41M Buy
+410,043
New +$1.45M ﹤0.01% 2490
2021
Q4
Sell
-910,153
Closed -$3.32M 4136
2021
Q3
$3.32M Sell
910,153
-329,790
-27% -$1.23M ﹤0.01% 1708
2021
Q2
$5.02M Buy
+1,239,943
New +$4.86M 0.01% 1640
2021
Q1
Sell
-594,343
Closed -$2.35M 3596
2020
Q4
$2.35M Buy
+594,343
New +$2.48M ﹤0.01% 2024
2018
Q4
Sell
-29,043
Closed -$100K 3538
2018
Q3
$100K Buy
+29,043
New +$154K ﹤0.01% 3245
2018
Q2
Sell
-370,401
Closed -$1.17M 3454
2018
Q1
$1.17M Buy
370,401
+210,410
+132% +$847K ﹤0.01% 2594
2017
Q4
$784K Sell
159,991
-917,500
-85% -$5.32M ﹤0.01% 2752
2017
Q3
$7.39M Sell
1,077,491
-538,200
-33% -$3.39M 0.01% 1517
2017
Q2
$10.6M Buy
+1,615,691
New +$11.3M 0.01% 1248
2016
Q4
Sell
-1,412,757
Closed -$15M 3389
2016
Q3
$15M Buy
+1,412,757
New +$14.1M 0.03% 896
2015
Q3
Sell
-1,907,498
Closed -$30.7M 3305
2015
Q2
$30.7M Buy
1,907,498
+654,100
+52% +$10.2M 0.07% 338
2015
Q1
$17.8M Buy
+1,253,398
New +$16.3M 0.04% 642
2013
Q4
Sell
-17,802
Closed -$157K 2976
2013
Q3
$157K Buy
+17,802
New +$143K ﹤0.01% 2628

Other funds holding OPK

Jim Simons's OPK Position: Q1 2026 in Review

Jim Simons opened a new position in Opko Health (OPK) in Q1 2026: 109,543 shares worth $125K. The stake represents ﹤0.01% of the portfolio and ranks #2995 among its holdings. This is a return to the name: Jim Simons previously reported a position in OPK as recently as Q3 2025.

Jim Simons first reported a position in OPK in Q3 2013 and has held it in 26 quarters since. The position peaked at $30.7M in Q2 2015. 236 funds tracked by Wall St. Rank hold OPK as of Q1 2026.

  • Jim Simons held 109,543 shares of Opko Health worth $125K as of Q1 2026.
  • Opko Health was a new Jim Simons position in Q1 2026.
  • Opko Health made up ﹤0.01% of Jim Simons's portfolio in Q1 2026, its #2995 holding.
  • Jim Simons first reported a position in Opko Health in Q3 2013 and has held it in 26 quarters since.
  • Jim Simons's Opko Health position peaked at $30.7M in Q2 2015.
  • 236 funds tracked by Wall St. Rank held Opko Health as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.