Jim Simons’s Milestone Pharmaceuticals MIST Stock Holding History

Jim Simons’s Portfolio MIST Stock Details MIST Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$154K	Buy	+129,705	New	+$227K	﹤0.01%	2960
2023 Q3	–	Sell	-108,766	Closed	-$310K	–	3932
2023 Q2	$310K	Buy	108,766 +16,966	+18%	+$64K	﹤0.01%	3111
2023 Q1	$362K	Buy	91,800 +24,600	+37%	+$89.9K	﹤0.01%	3036
2022 Q4	$266K	Buy	+67,200	New	+$354K	﹤0.01%	3278
2021 Q4	–	Sell	-26,400	Closed	-$151K	–	4106
2021 Q3	$151K	Sell	26,400 -81,154	-75%	-$458K	﹤0.01%	3258
2021 Q2	$592K	Sell	107,554 -108,846	-50%	-$617K	﹤0.01%	2898
2021 Q1	$1.25M	Buy	216,400 +52,400	+32%	+$384K	﹤0.01%	2507
2020 Q4	$1.1M	Buy	164,000 +148,900	+986%	+$997K	﹤0.01%	2457
2020 Q3	$111K	Buy	+15,100	New	+$108K	﹤0.01%	3205
2020 Q2	–	Sell	-10,242	Closed	-$19K	–	3648
2020 Q1	$19K	Buy	+10,242	New	+$177K	﹤0.01%	3375

Other funds holding MIST

PCML

Pavaki Capital Management LLC Pueblo, Colorado $287M AUM

RTW Investments New York $10B AUM 135.35% 1-Year Est. Return

PBM

Propel Bio Management Los Angeles, California $159M AUM 60.94% 1-Year Est. Return

Two Sigma Investments New York $124B AUM 33.93% 1-Year Est. Return

Goldman Sachs New York $871B AUM 31.28% 1-Year Est. Return

Marshall Wace London, United Kingdom $100B AUM 35.1% 1-Year Est. Return

Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

SAM

Simplify Asset Management Las Vegas, Nevada $7.19B AUM 6.88% 1-Year Est. Return

Point72 Asset Management Stamford, Connecticut $78.1B AUM 55.25% 1-Year Est. Return

Balyasny Asset Management Chicago, Illinois $77.1B AUM 42.89% 1-Year Est. Return

Jim Simons's MIST Position: Q1 2026 in Review

Jim Simons opened a new position in Milestone Pharmaceuticals (MIST) in Q1 2026: 129,705 shares worth $154K. The stake represents ﹤0.01% of the portfolio and ranks #2960 among its holdings. This is a return to the name: Jim Simons previously reported a position in MIST as recently as Q2 2023.

Jim Simons first reported a position in MIST in Q1 2020 and has held it in 10 quarters since. The position peaked at $1.25M in Q1 2021. 87 funds tracked by Wall St. Rank hold MIST as of Q1 2026.

Jim Simons held 129,705 shares of Milestone Pharmaceuticals worth $154K as of Q1 2026.
Milestone Pharmaceuticals was a new Jim Simons position in Q1 2026.
Milestone Pharmaceuticals made up ﹤0.01% of Jim Simons's portfolio in Q1 2026, its #2960 holding.
Jim Simons first reported a position in Milestone Pharmaceuticals in Q1 2020 and has held it in 10 quarters since.
Jim Simons's Milestone Pharmaceuticals position peaked at $1.25M in Q1 2021.
87 funds tracked by Wall St. Rank held Milestone Pharmaceuticals as of Q1 2026.

Based on Renaissance Technologies's 13F filing for Q1 2026, filed 14 May 2026.