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Jefferies Financial Group’s Structure Therapeutics GPCR Stock Holding History

Jefferies Financial Group’s Portfolio GPCR Stock Details GPCR Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2025
Q1 		– Sell
-27,100
Closed -$735K – 1766
2024
Q4 		$735K Hold
27,100
– – ﹤0.01% 992
2024
Q3 		$1.19M Buy
+27,100
New +$1.05M 0.01% 743
2024
Q2 		– Sell
-46,900
Closed -$2.01M – 1575
2024
Q1 		$2.01M Buy
+46,900
New +$1.98M 0.02% 594

Other funds holding GPCR

Fidelity Investments
Fidelity Investments Boston, Massachusetts $2.3T AUM 54.33% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $580B AUM 38.23% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $11.1B AUM 207.82% 1-Year Est. Return
JT
Jupiter Topco New York $245B AUM
DTC
Deep Track Capital Greenwich, Connecticut $6.87B AUM 205.24% 1-Year Est. Return
BI
BVF Inc San Francisco, California $3.91B AUM 304.52% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.89T AUM 35.08% 1-Year Est. Return
O
OrbiMed New York $5.4B AUM 163.13% 1-Year Est. Return
Principal Financial Group
Principal Financial Group Des Moines, Iowa $204B AUM 27.99% 1-Year Est. Return
American Century Companies
American Century Companies Kansas City, Missouri $226B AUM 44.75% 1-Year Est. Return

Jefferies Financial Group's GPCR Position: Q2 2026 in Review

Jefferies Financial Group reduced its Structure Therapeutics (GPCR) stake by 35% in Q2 2026, selling an estimated $972K and leaving 40,625 shares worth $2.18M. The position accounts for 0.01% of the portfolio, ranked #664.

Jefferies Financial Group first reported a position in GPCR in Q1 2024 and has held it in 7 quarters since. The position peaked at $7.16M in Q4 2025. 191 funds tracked by Wall St. Rank hold GPCR as of Q2 2026.

  • Jefferies Financial Group held 40,625 shares of Structure Therapeutics worth $2.18M as of Q2 2026.
  • Jefferies Financial Group sold 21,967 Structure Therapeutics shares in Q2 2026, an estimated $972K.
  • Structure Therapeutics made up 0.01% of Jefferies Financial Group's portfolio in Q2 2026, its #664 holding.
  • Jefferies Financial Group first reported a position in Structure Therapeutics in Q1 2024 and has held it in 7 quarters since.
  • Jefferies Financial Group's Structure Therapeutics position peaked at $7.16M in Q4 2025.
  • 191 funds tracked by Wall St. Rank held Structure Therapeutics as of Q2 2026.

Based on Jefferies Financial Group's 13F filing for Q2 2026, filed 17 Aug 2026.