Jane Street’s Xenon Pharmaceuticals XENE Stock Holding History

Jane Street’s Portfolio XENE Stock Details XENE Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2026 Q1	$7.76M	Buy	133,500 +128,300	+2,467%	+$5.91M	﹤0.01%	2859
2025 Q4	$233K	Buy	+5,200	New	+$218K	﹤0.01%	9407
2025 Q2	–	Sell	-24,200	Closed	-$812K	–	11088
2025 Q1	$812K	Buy	24,200 +14,900	+160%	+$566K	﹤0.01%	5966
2024 Q4	$365K	Sell	9,300 -41,100	-82%	-$1.7M	﹤0.01%	7400
2024 Q3	$1.98M	Sell	50,400 -98,600	-66%	-$3.98M	﹤0.01%	4494
2024 Q2	$5.81M	Buy	149,000 +111,400	+296%	+$4.45M	﹤0.01%	2751
2024 Q1	$1.62M	Buy	37,600 +25,800	+219%	+$1.19M	﹤0.01%	4506
2023 Q4	$544K	Sell	11,800 -46,100	-80%	-$1.63M	﹤0.01%	6617
2023 Q3	$1.98M	Buy	57,900 +2,000	+4%	+$74.8K	﹤0.01%	4072
2023 Q2	$2.15M	Sell	55,900 -8,800	-14%	-$350K	﹤0.01%	4064
2023 Q1	$2.32M	Buy	64,700 +57,000	+740%	+$2.11M	﹤0.01%	3567
2022 Q4	$304K	Buy	+7,700	New	+$280K	﹤0.01%	6999
2022 Q3	–	Sell	-8,200	Closed	-$249K	–	10589
2022 Q2	$249K	Buy	+8,200	New	+$248K	﹤0.01%	7886

Other funds holding XENE

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

PCH

Polar Capital Holdings London, United Kingdom $28.2B AUM 115.26% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

Capital International Investors Los Angeles, California $427B AUM 29.17% 1-Year Est. Return

Citadel Advisors Miami, Florida $618B AUM 30.34% 1-Year Est. Return

JP Morgan Chase New York $1.56T AUM 27.86% 1-Year Est. Return

Jane Street's XENE Position: Q1 2026 in Review

Jane Street opened a new position in Xenon Pharmaceuticals (XENE) in Q1 2026: 3,468 shares worth $202K. The stake represents ﹤0.01% of the portfolio and ranks #10131 among its holdings. This is a return to the name: Jane Street previously reported a position in XENE as recently as Q3 2025.

Jane Street first reported a position in XENE in Q1 2022 and has held it in 13 quarters since. The position peaked at $3.61M in Q3 2025. 290 funds tracked by Wall St. Rank hold XENE as of Q1 2026.

Jane Street held 3,468 shares of Xenon Pharmaceuticals worth $202K as of Q1 2026.
Xenon Pharmaceuticals was a new Jane Street position in Q1 2026.
Xenon Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #10131 holding.
Jane Street first reported a position in Xenon Pharmaceuticals in Q1 2022 and has held it in 13 quarters since.
Jane Street's Xenon Pharmaceuticals position peaked at $3.61M in Q3 2025.
290 funds tracked by Wall St. Rank held Xenon Pharmaceuticals as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.