Jane Street
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Jane Street’s Rhythm Pharmaceuticals RYTM Stock Holding History

Jane Street’s Portfolio RYTM Stock Details RYTM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q2 		$3.01M Sell
27,100
-19,400
-42% -$1.75M ﹤0.01% 4506
2026
Q1 		$4.04M Sell
46,500
-91,200
-66% -$8.87M ﹤0.01% 3832
2025
Q4 		$14.7M Buy
137,700
+64,700
+89% +$6.86M ﹤0.01% 1885
2025
Q3 		$7.37M Buy
73,000
+3,400
+5% +$316K ﹤0.01% 2841
2025
Q2 		$4.4M Sell
69,600
-100,500
-59% -$6.15M ﹤0.01% 3174
2025
Q1 		$9.01M Buy
170,100
+72,100
+74% +$4M ﹤0.01% 2133
2024
Q4 		$5.49M Sell
98,000
-88,300
-47% -$4.88M ﹤0.01% 2540
2024
Q3 		$9.76M Buy
186,300
+103,600
+125% +$4.96M ﹤0.01% 1934
2024
Q2 		$3.4M Sell
82,700
-9,300
-10% -$371K ﹤0.01% 3597
2024
Q1 		$3.99M Sell
92,000
-129,000
-58% -$5.65M ﹤0.01% 2964
2023
Q4 		$10.2M Buy
221,000
+60,000
+37% +$1.89M ﹤0.01% 1934
2023
Q3 		$3.69M Buy
161,000
+134,500
+508% +$3.01M ﹤0.01% 3057
2023
Q2 		$437K Buy
26,500
+2,300
+10% +$41.5K ﹤0.01% 6522
2023
Q1 		$432K Sell
24,200
-59,800
-71% -$1.5M ﹤0.01% 6562
2022
Q4 		$2.45M Sell
84,000
-209,500
-71% -$5.38M ﹤0.01% 3540
2022
Q3 		$7.19M Buy
+293,500
New +$5.46M ﹤0.01% 2087

Other funds holding RYTM

RCM
RA Capital Management Boston, Massachusetts $11.5B AUM 168.77% 1-Year Est. Return
BlackRock
BlackRock New York $6.73T AUM 46.02% 1-Year Est. Return
BBA
Baker Bros. Advisors New York $20B AUM 154.41% 1-Year Est. Return
Primecap Management
Primecap Management Pasadena, California $169B AUM 114.72% 1-Year Est. Return
Vanguard Portfolio Management
Vanguard Portfolio Management Malvern, Pennsylvania $2.22T AUM
Vanguard Capital Management
Vanguard Capital Management Malvern, Pennsylvania $4.68T AUM
JP Morgan Chase
JP Morgan Chase New York $1.81T AUM 41.13% 1-Year Est. Return
PA
Perceptive Advisors New York $6.66B AUM 360.84% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $3.37T AUM 44.26% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $999B AUM 46.22% 1-Year Est. Return

Jane Street's RYTM Position: Q2 2026 in Review

Jane Street opened a new position in Rhythm Pharmaceuticals (RYTM) in Q2 2026: 2,710 shares worth $301K. The stake represents ﹤0.01% of the portfolio and ranks #9208 among its holdings. This is a return to the name: Jane Street previously reported a position in RYTM as recently as Q4 2025.

Jane Street first reported a position in RYTM in Q2 2018 and has held it in 19 quarters since. The position peaked at $8.47M in Q4 2023. 304 funds tracked by Wall St. Rank hold RYTM as of Q2 2026.

  • Jane Street held 2,710 shares of Rhythm Pharmaceuticals worth $301K as of Q2 2026.
  • Rhythm Pharmaceuticals was a new Jane Street position in Q2 2026.
  • Rhythm Pharmaceuticals made up ﹤0.01% of Jane Street's portfolio in Q2 2026, its #9208 holding.
  • Jane Street first reported a position in Rhythm Pharmaceuticals in Q2 2018 and has held it in 19 quarters since.
  • Jane Street's Rhythm Pharmaceuticals position peaked at $8.47M in Q4 2023.
  • 304 funds tracked by Wall St. Rank held Rhythm Pharmaceuticals as of Q2 2026.

Based on Jane Street's 13F filing for Q2 2026, filed 14 Aug 2026.