Jane Street
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Jane Street’s Disc Medicine IRON Stock Holding History

Jane Street’s Portfolio IRON Stock Details IRON Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		– Sell
-2,600
Closed -$206K – 12254
2025
Q4 		$206K Buy
+2,600
New +$220K ﹤0.01% 9657
2024
Q2 		– Sell
-25,500
Closed -$1.59M – 9773
2024
Q1 		$1.59M Buy
+25,500
New +$1.65M ﹤0.01% 4549

Other funds holding IRON

Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
RCM
RA Capital Management Boston, Massachusetts $9.44B AUM 157.3% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
AVLSA
Atlas Venture Life Science Advisors Cambridge, Massachusetts $790M AUM 223.66% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
FLSM
Frazier Life Sciences Management Palo Alto, California $3.89B AUM 201.1% 1-Year Est. Return
TCM
TCG Crossover Management Palo Alto, California $3.5B AUM 1,165.83% 1-Year Est. Return

Jane Street's IRON Position: Q4 2025 in Review

Jane Street sold out of Disc Medicine (IRON) in Q4 2025, closing a stake of 21,274 shares — an estimated $1.8M sold.

Jane Street first reported a position in IRON in Q4 2021 and held it in 9 quarters. The position peaked at $2.54M in Q1 2024. 196 funds tracked by Wall St. Rank hold IRON as of Q4 2025.

  • Jane Street reported no remaining Disc Medicine position as of Q4 2025 after selling out during the quarter.
  • Jane Street sold 21,274 Disc Medicine shares in Q4 2025, an estimated $1.8M.
  • Jane Street first reported a position in Disc Medicine in Q4 2021 and held it in 9 quarters.
  • Jane Street's Disc Medicine position peaked at $2.54M in Q1 2024.
  • 196 funds tracked by Wall St. Rank held Disc Medicine as of Q4 2025.

Based on Jane Street's 13F filing for Q4 2025, filed 12 Feb 2026.