Jane Street
DFTX

Jane Street’s Definium Therapeutics DFTX Stock Holding History

Jane Street’s Portfolio DFTX Stock Details DFTX Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$4.92M Sell
260,241
-275,761
-51% -$4.68M ﹤0.01% 3548
2025
Q4 		$7.18M Buy
536,002
+261,154
+95% +$3.23M ﹤0.01% 2726
2025
Q3 		$3.24M Buy
274,848
+146,533
+114% +$1.37M ﹤0.01% 4096
2025
Q2 		$833K Buy
128,315
+54,326
+73% +$357K ﹤0.01% 5968
2025
Q1 		$433K Buy
73,989
+57,432
+347% +$411K ﹤0.01% 7137
2024
Q4 		$115K Sell
16,557
-14,164
-46% -$97.5K ﹤0.01% 8711
2024
Q3 		$175K Sell
30,721
-47,552
-61% -$331K ﹤0.01% 8732
2024
Q2 		$564K Sell
78,273
-294,186
-79% -$2.57M ﹤0.01% 6825
2024
Q1 		$3.5M Buy
372,459
+262,796
+240% +$1.5M ﹤0.01% 3162
2023
Q4 		$401K Buy
109,663
+93,079
+561% +$280K ﹤0.01% 7151
2023
Q3 		$52.2K Buy
+16,584
New +$68.2K ﹤0.01% 8144
2022
Q4 		– Sell
-41,563
Closed -$115K – 9749
2022
Q3 		$144K Buy
41,563
+28,030
+207% +$269K ﹤0.01% 8429
2022
Q2 		$129K Sell
13,533
-6,320
-32% -$80K ﹤0.01% 8504
2022
Q1 		$338K Buy
19,853
+8,173
+70% +$142K ﹤0.01% 8203
2021
Q4 		$241K Buy
11,680
+8,278
+243% +$264K ﹤0.01% 8538
2021
Q3 		$123K Sell
3,402
-38,089
-92% -$1.65M ﹤0.01% 9179
2021
Q2 		$2.16M Buy
+41,491
New +$2.18M ﹤0.01% 4195

Other funds holding DFTX

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
DCM
Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return
ACA
Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return
Janus Henderson Group
Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return
OCA
Octagon Capital Advisors New York $904M AUM 737.04% 1-Year Est. Return
CC
Commodore Capital New York $1.73B AUM 298.96% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Jane Street's DFTX Position: Q1 2026 in Review

Jane Street reduced its Definium Therapeutics (DFTX) stake by 51% in Q1 2026, selling an estimated $4.68M and leaving 260,241 shares worth $4.92M. The position accounts for ﹤0.01% of the portfolio, ranked #3548.

Jane Street first reported a position in DFTX in Q2 2021 and has held it in 17 quarters since. The position peaked at $7.18M in Q4 2025. 247 funds tracked by Wall St. Rank hold DFTX as of Q1 2026.

  • Jane Street held 260,241 shares of Definium Therapeutics worth $4.92M as of Q1 2026.
  • Jane Street sold 275,761 Definium Therapeutics shares in Q1 2026, an estimated $4.68M.
  • Definium Therapeutics made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #3548 holding.
  • Jane Street first reported a position in Definium Therapeutics in Q2 2021 and has held it in 17 quarters since.
  • Jane Street's Definium Therapeutics position peaked at $7.18M in Q4 2025.
  • 247 funds tracked by Wall St. Rank held Definium Therapeutics as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.