Jane Street
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Jane Street’s Axsome Therapeutics AXSM Stock Holding History

Jane Street’s Portfolio AXSM Stock Details AXSM Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$18.5M Sell
109,700
-7,900
-7% -$1.36M ﹤0.01% 1848
2025
Q4 		$21.5M Buy
117,600
+29,700
+34% +$4.15M ﹤0.01% 1566
2025
Q3 		$10.7M Sell
87,900
-35,800
-29% -$4.03M ﹤0.01% 2333
2025
Q2 		$12.9M Sell
123,700
-13,600
-10% -$1.44M ﹤0.01% 1873
2025
Q1 		$16M Sell
137,300
-258,100
-65% -$29.4M ﹤0.01% 1489
2024
Q4 		$33.5M Buy
395,400
+280,900
+245% +$25.8M 0.01% 910
2024
Q3 		$10.3M Buy
114,500
+42,500
+59% +$3.71M ﹤0.01% 1883
2024
Q2 		$5.8M Sell
72,000
-5,500
-7% -$407K ﹤0.01% 2755
2024
Q1 		$6.18M Sell
77,500
-51,400
-40% -$4.31M ﹤0.01% 2346
2023
Q4 		$10.3M Buy
128,900
+12,400
+11% +$829K ﹤0.01% 1922
2023
Q3 		$8.14M Sell
116,500
-69,700
-37% -$5.21M ﹤0.01% 2005
2023
Q2 		$13.4M Sell
186,200
-106,500
-36% -$7.86M ﹤0.01% 1605
2023
Q1 		$18.1M Buy
292,700
+39,600
+16% +$2.6M 0.01% 1079
2022
Q4 		$19.5M Buy
253,100
+71,500
+39% +$4.27M 0.01% 1030
2022
Q3 		$8.1M Sell
181,600
-120,600
-40% -$6.03M ﹤0.01% 1936
2022
Q2 		$11.6M Buy
302,200
+188,100
+165% +$5.95M ﹤0.01% 1572
2022
Q1 		$4.72M Sell
114,100
-522,500
-82% -$16.2M ﹤0.01% 3118
2021
Q4 		$24.1M Buy
636,600
+327,000
+106% +$12M 0.01% 1051
2021
Q3 		$10.2M Buy
309,600
+273,700
+762% +$10.7M ﹤0.01% 1779
2021
Q2 		$2.42M Buy
35,900
+18,400
+105% +$1.1M ﹤0.01% 3960
2021
Q1 		$991K Sell
17,500
-84,500
-83% -$5.94M ﹤0.01% 5474
2020
Q4 		$8.31M Sell
102,000
-31,000
-23% -$2.32M ﹤0.01% 1582
2020
Q3 		$9.48M Sell
133,000
-600
-0.4% -$46.8K 0.01% 1257
2020
Q2 		$11M Sell
133,600
-18,500
-12% -$1.42M 0.01% 1122
2020
Q1 		$8.95M Buy
152,100
+67,200
+79% +$5.48M 0.01% 824
2019
Q4 		$8.78M Buy
+84,900
New +$3.43M 0.01% 719
2019
Q2 		– Sell
-45,000
Closed -$640K – 5117
2019
Q1 		$640K Buy
+45,000
New +$418K ﹤0.01% 3372

Other funds holding AXSM

BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
VPM
Vanguard Portfolio Management Malvern, Pennsylvania $1.91T AUM
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
T. Rowe Price Associates
T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return
Invesco
Invesco Atlanta, Georgia $1.02T AUM 30.18% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Wellington Management Group
Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return
DTC
Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return
State Street
State Street Boston, Massachusetts $2.9T AUM 29.55% 1-Year Est. Return

Jane Street's AXSM Position: Q1 2026 in Review

Jane Street reduced its Axsome Therapeutics (AXSM) stake by 97% in Q1 2026, selling an estimated $23M and leaving 4,078 shares worth $689K. The position accounts for ﹤0.01% of the portfolio, ranked #7302.

Jane Street first reported a position in AXSM in Q1 2019 and has held it in 28 quarters since. The position peaked at $25.1M in Q4 2025. 409 funds tracked by Wall St. Rank hold AXSM as of Q1 2026.

  • Jane Street held 4,078 shares of Axsome Therapeutics worth $689K as of Q1 2026.
  • Jane Street sold 133,205 Axsome Therapeutics shares in Q1 2026, an estimated $23M.
  • Axsome Therapeutics made up ﹤0.01% of Jane Street's portfolio in Q1 2026, its #7302 holding.
  • Jane Street first reported a position in Axsome Therapeutics in Q1 2019 and has held it in 28 quarters since.
  • Jane Street's Axsome Therapeutics position peaked at $25.1M in Q4 2025.
  • 409 funds tracked by Wall St. Rank held Axsome Therapeutics as of Q1 2026.

Based on Jane Street's 13F filing for Q1 2026, filed 12 May 2026.