Caption Management’s Structure Therapeutics GPCR Stock Holding History

Caption Management’s Portfolio GPCR Stock Details GPCR Fund Activity

Bought

Maintained

Sold

Quarter	Market Value	Status	Shares	Change in Stake	Trade Value	Portfolio Weight	Portfolio Position
2025 Q4	–	Sell	-159,400	Closed	-$4.46M	–	1770
2025 Q3	$4.46M	Buy	159,400 +97,500	+158%	+$1.94M	0.03%	530
2025 Q2	$1.28M	Buy	61,900 +35,000	+130%	+$770K	0.01%	864
2025 Q1	$466K	Buy	26,900 +15,000	+126%	+$367K	﹤0.01%	1118
2024 Q4	$323K	Sell	11,900 -50,000	-81%	-$1.77M	﹤0.01%	1197
2024 Q3	$2.72M	Buy	61,900 +50,000	+420%	+$1.93M	0.04%	467
2024 Q2	$467K	Buy	+11,900	New	+$489K	0.01%	819
2024 Q1	–	Sell	-91,000	Closed	-$3.71M	–	1392
2023 Q4	$3.71M	Buy	+91,000	New	+$5.21M	0.05%	435

Other funds holding GPCR

Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return

Wellington Management Group Boston, Massachusetts $535B AUM 26.23% 1-Year Est. Return

ACA

Avoro Capital Advisors New York $10.2B AUM 149.19% 1-Year Est. Return

Janus Henderson Group London, United Kingdom $209B AUM 37.72% 1-Year Est. Return

DTC

Deep Track Capital Greenwich, Connecticut $6.12B AUM 144% 1-Year Est. Return

BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return

Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return

T. Rowe Price Associates Baltimore, Maryland $865B AUM 30.76% 1-Year Est. Return

DCM

Driehaus Capital Management Chicago, Illinois $13.6B AUM 173.98% 1-Year Est. Return

BBA

Baker Bros. Advisors New York $17.4B AUM 131.5% 1-Year Est. Return

Caption Management's GPCR Position: Q4 2025 in Review

Caption Management sold out of Structure Therapeutics (GPCR) in Q4 2025, closing a stake of 56,682 shares — an estimated $1.59M sold.

Caption Management first reported a position in GPCR in Q1 2024 and held it in 7 quarters. The position peaked at $3M in Q1 2024. 197 funds tracked by Wall St. Rank hold GPCR as of Q4 2025.

Caption Management reported no remaining Structure Therapeutics position as of Q4 2025 after selling out during the quarter.
Caption Management sold 56,682 Structure Therapeutics shares in Q4 2025, an estimated $1.59M.
Caption Management first reported a position in Structure Therapeutics in Q1 2024 and held it in 7 quarters.
Caption Management's Structure Therapeutics position peaked at $3M in Q1 2024.
197 funds tracked by Wall St. Rank held Structure Therapeutics as of Q4 2025.

Based on Caption Management's 13F filing for Q4 2025, filed 17 Feb 2026.