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Large Cap Biotechnology
Stocks Ranked by
Market Capitalization

Name Market cap Price Price
change %
SMMT icon
26
Summit Therapeutics
SMMT
$10.7B
$10.7B $13.36 4.95%
IONS icon
27
Ionis Pharmaceuticals
IONS
$10.6B
$10.6B $63.57 2.47%
KRYS icon
28
Krystal Biotech
KRYS
$10.5B
$10.5B $356.19 4.23%
KYMR icon
29
Kymera Therapeutics
KYMR
$10.5B
$10.5B $126.64 4.62%
ABVX
30
Abivax
ABVX
$10.3B
$10.3B $117.93 1.53%
PRAX icon
31
Praxis Precision Medicines
PRAX
$10.3B
$10.3B $368.02 0%
APGE icon
32
Apogee Therapeutics
APGE
$10.2B
$10.2B $134.85 0.04%

Large Cap Biotechnology Stocks at a Glance

Biotechnology companies research and develop novel drugs and therapies, often with no products yet on the market. Clinical-trial readouts and regulatory decisions drive binary stock moves, making pipeline breadth, cash runway, and partnership deals the key variables.

There are 32 large cap Biotechnology stocks — companies in the Biotechnology industry with a market cap between $10B and $200B — worth a combined $862B.

The largest by market cap are Vertex Pharmaceuticals (VRTX) at $140B, Regeneron Pharmaceuticals (REGN) at $85.8B and argenx (ARGX) at $63.8B.

Among institutional investors, Revolution Medicines (RVMD) drew the most net new fund positions in Q2 2026: 243 funds opened new positions, taking total fund holders up 176 (34%) quarter-over-quarter.

Market caps and prices updated daily; fund activity based on aggregated SEC 13F filings for Q2 2026.