Zymeworks
ZYME
184 hedge funds and large institutions have $841M invested in Zymeworks in 2025 Q1 according to their latest regulatory filings, with 30 funds opening new positions, 60 increasing their positions, 65 reducing their positions, and 17 closing their positions.
1,070% more call options, than puts
Call options by funds: $3.46M | Put options by funds: $296K
76% more first-time investments, than exits
New positions opened: 30 | Existing positions closed: 17
7% more funds holding
Funds holding: 172 → 184 (+12)
4.94% more ownership
Funds ownership: 96.52% → 101.45% (+4.9%)
0% more funds holding in top 10
Funds holding in top 10: 5 → 5 (0)
8% less repeat investments, than reductions
Existing positions increased: 60 | Existing positions reduced: 65
14% less capital invested
Capital invested by funds: $973M → $841M (-$132M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UBS AM
Chicago,
Illinois
|
+$34.3M |
| 2 |
EC
EcoR1 Capital
San Francisco,
California
|
+$30.4M |
| 3 |
Blackstone Inc
New York
|
+$11.1M |
| 4 |
RCMNY
Rubric Capital Management (New York)
New York
|
+$5.74M |
| 5 |
VPC
Vestal Point Capital
New York
|
+$4.3M |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
FCM
Farallon Capital Management
San Francisco,
California
|
-$12.7M |
| 2 |
Vanguard Group
Malvern,
Pennsylvania
|
-$9.9M |
| 3 |
Point72 Asset Management
Stamford,
Connecticut
|
-$4.83M |
| 4 |
Jacobs Levy Equity Management
Florham Park,
New Jersey
|
-$4.69M |
| 5 |
SB
Samsara BioCapital
Palo Alto,
California
|
-$4.55M |
ZYME Hedge Fund Activity: Q1 2025 in Review
184 of the 7,459 institutional investors tracked by Wall St. Rank reported a position in Zymeworks (ZYME) for Q1 2025, worth a combined $841M — down 14% from $973M a quarter earlier.
Buyers outnumbered sellers: 30 funds opened new ZYME positions and 17 closed out — a net gain of 13 holders — while 60 added to existing stakes and 65 trimmed.
The largest buyer was UBS AM, adding an estimated $34.3M. The largest seller was Farallon Capital Management, cutting an estimated $12.7M.
- 184 institutional investors held Zymeworks (ZYME) as of Q1 2025, up from 172 in Q4 2024.
- Funds reported $841M of Zymeworks stock for Q1 2025, down 14% quarter-over-quarter.
- 30 funds opened new Zymeworks positions in Q1 2025 and 17 closed out, a net change of +13 holders.
- The largest Zymeworks buyer in Q1 2025 was UBS AM, an estimated $34.3M added.
- The largest Zymeworks seller in Q1 2025 was Farallon Capital Management, an estimated $12.7M sold.
Based on aggregated 13F filings for Q1 2025.