|
1
|
BVF Inc
San Francisco,
California
|
$78.8M
|
+$2.93M
|
+156,086
|
+4%
|
|
|
2
|
Opaleye Management
Boston,
Massachusetts
|
$8.57M
|
+$743K
|
+39,620
|
+10%
|
|
|
3
|
|
$8.48M
|
+$46.8K
|
+2,499
|
+0.6%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$6.4M
|
+$646K
|
+34,453
|
+11%
|
|
|
5
|
Stonepine Capital Management
Bend,
Oregon
|
$2.83M
|
–
|
–
|
–
|
|
|
6
|
Northern Trust
Chicago,
Illinois
|
$2.35M
|
-$11.7K
|
-623
|
-0.5%
|
|
|
7
|
Geode Capital Management
Boston,
Massachusetts
|
$1.88M
|
+$35.6K
|
+1,899
|
+2%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$1.29M
|
+$54.9K
|
+2,931
|
+4%
|
|
|
9
|
Bank of New York Mellon
New York
|
$1.13M
|
+$1.03K
|
+55
|
+0.1%
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$957K
|
–
|
–
|
–
|
|
|
11
|
|
$822K
|
+$410K
|
+21,866
|
+100%
|
|
|
12
|
RBF Capital
San Francisco,
California
|
$655K
|
–
|
–
|
–
|
|
|
13
|
Renaissance Technologies
New York
|
$597K
|
-$1.04M
|
-55,669
|
-64%
|
|
|
14
|
Marshall Wace
London,
United Kingdom
|
$590K
|
-$87.4K
|
-4,664
|
-13%
|
|
|
15
|
Winton Group
London,
United Kingdom
|
$345K
|
-$119K
|
-6,359
|
-26%
|
|
|
16
|
Charles Schwab
San Francisco,
California
|
$289K
|
-$19.6K
|
-1,043
|
-6%
|
|
|
17
|
Two Sigma Investments
New York
|
$268K
|
+$266K
|
+14,201
|
New
|
|
|
18
|
ALPS Advisors
Denver,
Colorado
|
$265K
|
-$18.4K
|
-984
|
-7%
|
|
|
19
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$239K
|
–
|
–
|
–
|
|
|
20
|
Nuveen
Charlotte,
North Carolina
|
$226K
|
–
|
–
|
–
|
|
|
21
|
California Public Employees Retirement System
Sacramento,
California
|
$217K
|
–
|
–
|
–
|
|
|
22
|
|
$215K
|
–
|
–
|
–
|
|
|
23
|
Millennium Management
New York
|
$209K
|
-$490K
|
-26,154
|
-70%
|
|
|
24
|
Wells Fargo
San Francisco,
California
|
$201K
|
-$21.8K
|
-1,164
|
-10%
|
|
|
25
|
|
$188K
|
-$53.8K
|
-2,869
|
-22%
|
|
