|
1
|
BVF Inc
San Francisco,
California
|
$78.7M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$25.2M
|
+$3.94M
|
+191,703
|
+20%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$8.46M
|
-$521K
|
-25,385
|
-6%
|
|
|
4
|
Opaleye Management
Boston,
Massachusetts
|
$5.86M
|
-$163K
|
-7,950
|
-3%
|
|
|
5
|
|
$3.63M
|
-$6.13M
|
-298,438
|
-65%
|
|
|
6
|
Rubric Capital Management (New York)
New York
|
$3.33M
|
+$3.07M
|
+149,446
|
New
|
|
|
7
|
Geode Capital Management
Boston,
Massachusetts
|
$2.27M
|
-$961K
|
-46,819
|
-31%
|
|
|
8
|
Millennium Management
New York
|
$1.98M
|
+$1.31M
|
+63,944
|
+255%
|
|
|
9
|
Bank of New York Mellon
New York
|
$1.04M
|
-$335K
|
-16,342
|
-26%
|
|
|
10
|
Stonepine Capital Management
Bend,
Oregon
|
$1.02M
|
+$187K
|
+9,107
|
+25%
|
|
|
11
|
|
$1M
|
+$866K
|
+42,184
|
+1,541%
|
|
|
12
|
Northern Trust
Chicago,
Illinois
|
$977K
|
-$865K
|
-42,128
|
-49%
|
|
|
13
|
State Street
Boston,
Massachusetts
|
$916K
|
-$1.85M
|
-90,249
|
-69%
|
|
|
14
|
RBF Capital
San Francisco,
California
|
$886K
|
+$103K
|
+5,000
|
+14%
|
|
|
15
|
Renaissance Technologies
New York
|
$731K
|
+$673K
|
+32,800
|
New
|
|
|
16
|
|
$566K
|
+$521K
|
+25,400
|
New
|
|
|
17
|
Citadel Advisors
Miami,
Florida
|
$507K
|
+$467K
|
+22,746
|
New
|
|
|
18
|
Pinz Capital Management
New York
|
$449K
|
+$414K
|
+20,160
|
New
|
|
|
19
|
Trexquant Investment
Stamford,
Connecticut
|
$337K
|
+$130K
|
+6,315
|
+72%
|
|
|
20
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$297K
|
+$97.3K
|
+4,740
|
+55%
|
|
|
21
|
|
$222K
|
–
|
–
|
–
|
|
|
22
|
Macquarie Group
Sydney, NSW 2000,
Australia
|
$77K
|
–
|
–
|
–
|
|
|
23
|
Lazard Asset Management
New York
|
$75K
|
+$25.3K
|
+1,231
|
+57%
|
|
|
24
|
BNP Paribas Financial Markets
Paris,
France
|
$54.6K
|
+$22.6K
|
+1,102
|
+82%
|
|
|
25
|
Bank of America
Charlotte,
North Carolina
|
$48K
|
-$3K
|
-146
|
-6%
|
|
