Two Sigma Investments
XOMA

Two Sigma Investments’s Xoma XOMA Stock Holding History

Two Sigma Investments’s Portfolio XOMA Stock Details XOMA Fund Activity
Bought
Maintained
Sold
Quarter Market Value Status Shares Change in
Stake 		Trade Value Portfolio Weight Portfolio Position
2026
Q1 		$818K Buy
26,075
+16,360
+168% +$438K ﹤0.01% 3412
2025
Q4 		$258K Buy
+9,715
New +$313K ﹤0.01% 3652
2021
Q2 		– Sell
-10,856
Closed -$443K – 4642
2021
Q1 		$443K Buy
+10,856
New +$420K ﹤0.01% 3042
2020
Q4 		– Sell
-14,201
Closed -$268K – 3832
2020
Q3 		$268K Buy
+14,201
New +$266K ﹤0.01% 2650
2020
Q2 		– Sell
-10,299
Closed -$210K – 3604
2020
Q1 		$210K Sell
10,299
-8,724
-46% -$201K ﹤0.01% 2620
2019
Q4 		$519K Buy
+19,023
New +$426K ﹤0.01% 2771
2018
Q1 		– Sell
-88,692
Closed -$3.16M – 3568
2017
Q4 		$3.16M Buy
88,692
+77,843
+718% +$2.11M 0.01% 1171
2017
Q3 		$213K Buy
+10,849
New +$121K ﹤0.01% 2568
2016
Q2 		– Sell
-7,878
Closed -$122K – 3291
2016
Q1 		$122K Buy
7,878
+4,686
+147% +$84.4K ﹤0.01% 2669
2015
Q4 		$85K Sell
3,192
-15,216
-83% -$389K ﹤0.01% 2589
2015
Q3 		$277K Buy
+18,408
New +$581K ﹤0.01% 1823
2015
Q1 		– Sell
-28,063
Closed -$2.02M – 2896
2014
Q4 		$2.02M Buy
+28,063
New +$2.4M 0.01% 1023
2014
Q1 		– Sell
-6,903
Closed -$929K – 2300
2013
Q4 		$929K Buy
+6,903
New +$696K 0.01% 1364

Other funds holding XOMA

BI
BVF Inc San Francisco, California $3.14B AUM 249.53% 1-Year Est. Return
Morgan Stanley
Morgan Stanley New York $1.66T AUM 25.57% 1-Year Est. Return
Fidelity Investments
Fidelity Investments Boston, Massachusetts $1.9T AUM 41.92% 1-Year Est. Return
BlackRock
BlackRock New York $5.72T AUM 30.48% 1-Year Est. Return
WP
Woodline Partners San Francisco, California $26.4B AUM 44.85% 1-Year Est. Return
VCM
Vanguard Capital Management Malvern, Pennsylvania $4.04T AUM
OM
Opaleye Management Boston, Massachusetts $759M AUM 124.8% 1-Year Est. Return
GKIM
GW&K Investment Management Boston, Massachusetts $11.3B AUM 31.98% 1-Year Est. Return
Geode Capital Management
Geode Capital Management Boston, Massachusetts $1.61T AUM 30.72% 1-Year Est. Return
Millennium Management
Millennium Management New York $240B AUM 35.51% 1-Year Est. Return

Two Sigma Investments's XOMA Position: Q1 2026 in Review

Two Sigma Investments increased its Xoma (XOMA) stake by 168% in Q1 2026, buying an estimated $438K and bringing the position to 26,075 shares worth $818K. The position accounts for ﹤0.01% of the portfolio, ranked #3412.

Two Sigma Investments first reported a position in XOMA in Q4 2013 and has held it in 13 quarters since. The position peaked at $3.16M in Q4 2017. 85 funds tracked by Wall St. Rank hold XOMA as of Q1 2026.

  • Two Sigma Investments held 26,075 shares of Xoma worth $818K as of Q1 2026.
  • Two Sigma Investments bought 16,360 Xoma shares in Q1 2026, an estimated $438K.
  • Xoma made up ﹤0.01% of Two Sigma Investments's portfolio in Q1 2026, its #3412 holding.
  • Two Sigma Investments first reported a position in Xoma in Q4 2013 and has held it in 13 quarters since.
  • Two Sigma Investments's Xoma position peaked at $3.16M in Q4 2017.
  • 85 funds tracked by Wall St. Rank held Xoma as of Q1 2026.

Based on Two Sigma Investments's 13F filing for Q1 2026, filed 15 May 2026.