|
1
|
|
$157M
|
+$13.8M
|
+1,108,700
|
+9%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$125M
|
+$1.49M
|
+119,700
|
+1%
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$86M
|
–
|
–
|
–
|
|
|
4
|
|
$81.7M
|
–
|
–
|
–
|
|
|
5
|
RA Capital Management
Boston,
Massachusetts
|
$59.1M
|
+$60.8M
|
+4,897,237
|
New
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$52.5M
|
-$1.93M
|
-155,218
|
-3%
|
|
|
7
|
Vanguard Portfolio Management
Malvern,
Pennsylvania
|
$42.2M
|
+$43.4M
|
+3,500,342
|
New
|
|
|
8
|
Vanguard Capital Management
Malvern,
Pennsylvania
|
$37.4M
|
+$38.5M
|
+3,101,647
|
New
|
|
|
9
|
TCG Crossover Management
Palo Alto,
California
|
$29.6M
|
–
|
–
|
–
|
|
|
10
|
EcoR1 Capital
San Francisco,
California
|
$26.3M
|
-$13.3M
|
-1,068,112
|
-33%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$21.9M
|
+$778K
|
+62,659
|
+4%
|
|
|
12
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$18.8M
|
-$513K
|
-41,342
|
-3%
|
|
|
13
|
|
$18.8M
|
+$615K
|
+49,563
|
+3%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$15.6M
|
+$566K
|
+45,599
|
+4%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$13.3M
|
–
|
–
|
–
|
|
|
16
|
UBS Group
Zurich,
Switzerland
|
$13.1M
|
+$5.51M
|
+444,398
|
+70%
|
|
|
17
|
Legal & General Group
London,
United Kingdom
|
$12.9M
|
-$2.99M
|
-241,308
|
-18%
|
|
|
18
|
Two Sigma Investments
New York
|
$9.71M
|
+$6.66M
|
+536,684
|
+200%
|
|
|
19
|
|
$9.21M
|
+$131K
|
+10,535
|
+1%
|
|
|
20
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$9.02M
|
–
|
–
|
–
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$8.98M
|
+$867K
|
+69,862
|
+10%
|
|
|
22
|
Jefferies Financial Group
New York
|
$8.69M
|
–
|
–
|
–
|
|
|
23
|
Charles Schwab
San Francisco,
California
|
$8.4M
|
-$44.4K
|
-3,581
|
-0.5%
|
|
|
24
|
Panagora Asset Management
Boston,
Massachusetts
|
$7.49M
|
+$459K
|
+36,978
|
+6%
|
|
|
25
|
Millennium Management
New York
|
$7.35M
|
+$191K
|
+15,353
|
+3%
|
|
