|
1
|
|
$183M
|
+$1.79M
|
+119,991
|
+1%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$156M
|
-$6.82M
|
-456,700
|
-4%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$110M
|
+$922K
|
+61,692
|
+0.9%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$109M
|
+$65.6M
|
+4,393,579
|
+160%
|
|
|
5
|
|
$104M
|
+$8.31M
|
+556,407
|
+9%
|
|
|
6
|
State Street
Boston,
Massachusetts
|
$69M
|
+$12.5M
|
+833,423
|
+23%
|
|
|
7
|
EcoR1 Capital
San Francisco,
California
|
$49.8M
|
-$43.2M
|
-2,893,655
|
-47%
|
|
|
8
|
TCG Crossover Management
Palo Alto,
California
|
$37.5M
|
–
|
–
|
–
|
|
|
9
|
Geode Capital Management
Boston,
Massachusetts
|
$26.8M
|
+$360K
|
+24,093
|
+1%
|
|
|
10
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$24.5M
|
-$1.37M
|
-91,530
|
-5%
|
|
|
11
|
|
$23.1M
|
+$9.08M
|
+607,890
|
+67%
|
|
|
12
|
Defilade Capital Management
Emeryville,
California
|
$21.7M
|
+$21.1M
|
+1,414,755
|
New
|
|
|
13
|
Legal & General Group
London,
United Kingdom
|
$20M
|
+$524K
|
+35,088
|
+3%
|
|
|
14
|
Dimensional Fund Advisors
Austin,
Texas
|
$19.1M
|
-$5.08M
|
-339,675
|
-21%
|
|
|
15
|
Baker Bros. Advisors
New York
|
$16.9M
|
–
|
–
|
–
|
|
|
16
|
|
$11.5M
|
-$3.95M
|
-264,195
|
-26%
|
|
|
17
|
Johnson & Johnson
New Brunswick,
New Jersey
|
$11.5M
|
–
|
–
|
–
|
|
|
18
|
Jefferies Financial Group
New York
|
$11M
|
+$9.27M
|
+620,440
|
+620%
|
|
|
19
|
Lynx1 Capital Management
San Juan,
Puerto Rico
|
$10.8M
|
+$10.5M
|
+705,558
|
New
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$10.7M
|
+$182K
|
+12,166
|
+2%
|
|
|
21
|
Northern Trust
Chicago,
Illinois
|
$10.3M
|
-$561K
|
-37,544
|
-5%
|
|
|
22
|
UBS Group
Zurich,
Switzerland
|
$9.77M
|
-$8.03M
|
-537,246
|
-46%
|
|
|
23
|
Bank of America
Charlotte,
North Carolina
|
$9.64M
|
-$1.86M
|
-124,421
|
-17%
|
|
|
24
|
Millennium Management
New York
|
$9.1M
|
-$1.62M
|
-108,139
|
-15%
|
|
|
25
|
Panagora Asset Management
Boston,
Massachusetts
|
$8.94M
|
-$557K
|
-37,251
|
-6%
|
|
