|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$305M
|
+$2.25M
|
+61,233
|
+0.7%
|
|
|
2
|
Primecap Management
Pasadena,
California
|
$275M
|
-$321K
|
-8,760
|
-0.1%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$241M
|
+$1.09M
|
+29,595
|
+0.4%
|
|
|
4
|
Vanguard Group
Malvern,
Pennsylvania
|
$156M
|
+$3.98M
|
+108,385
|
+3%
|
|
|
5
|
|
$150M
|
+$3.7M
|
+100,924
|
+2%
|
|
|
6
|
Redmile Group
San Francisco,
California
|
$112M
|
+$2M
|
+54,560
|
+2%
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$50.7M
|
+$1.6M
|
+43,679
|
+3%
|
|
|
8
|
EcoR1 Capital
San Francisco,
California
|
$35.8M
|
+$36.3M
|
+989,018
|
New
|
|
|
9
|
|
$28.3M
|
+$7.93M
|
+216,061
|
+38%
|
|
|
10
|
Northern Trust
Chicago,
Illinois
|
$21.8M
|
+$64.2K
|
+1,751
|
+0.3%
|
|
|
11
|
BVF Inc
San Francisco,
California
|
$21.5M
|
-$8.96M
|
-244,073
|
-29%
|
|
|
12
|
Geode Capital Management
Boston,
Massachusetts
|
$19.9M
|
+$1.4M
|
+38,127
|
+7%
|
|
|
13
|
|
$18.1M
|
–
|
–
|
–
|
|
|
14
|
Franklin Resources
San Mateo,
California
|
$17.1M
|
-$843K
|
-22,985
|
-5%
|
|
|
15
|
First Light Asset Management
Edina,
Minnesota
|
$16.8M
|
-$69.1K
|
-1,883
|
-0.4%
|
|
|
16
|
Baker Bros. Advisors
New York
|
$15.9M
|
-$5.96M
|
-162,309
|
-27%
|
|
|
17
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$15.8M
|
+$225K
|
+6,145
|
+1%
|
|
|
18
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$15.7M
|
+$274K
|
+7,458
|
+2%
|
|
|
19
|
Dimensional Fund Advisors
Austin,
Texas
|
$14.4M
|
+$4.38M
|
+119,347
|
+43%
|
|
|
20
|
|
$10.5M
|
-$1.79M
|
-48,879
|
-14%
|
|
|
21
|
Charles Schwab
San Francisco,
California
|
$9.37M
|
+$56.8K
|
+1,547
|
+0.6%
|
|
|
22
|
|
$8.9M
|
-$183K
|
-4,993
|
-2%
|
|
|
23
|
|
$8.03M
|
+$130K
|
+3,530
|
+2%
|
|
|
24
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$7.9M
|
+$319K
|
+8,683
|
+4%
|
|
|
25
|
Bank of New York Mellon
New York
|
$7.52M
|
-$505K
|
-13,772
|
-6%
|
|
