|
1
|
|
$403M
|
+$10.2M
|
+247,457
|
+3%
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$376M
|
+$1.32M
|
+31,992
|
+0.4%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$262M
|
+$5.4M
|
+130,490
|
+2%
|
|
|
4
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$248M
|
+$260K
|
+6,283
|
+0.1%
|
|
|
5
|
Primecap Management
Pasadena,
California
|
$233M
|
-$2.8M
|
-67,710
|
-1%
|
|
|
6
|
EcoR1 Capital
San Francisco,
California
|
$198M
|
–
|
–
|
–
|
|
|
7
|
State Street
Boston,
Massachusetts
|
$107M
|
+$2.13M
|
+51,392
|
+2%
|
|
|
8
|
BVF Inc
San Francisco,
California
|
$55.2M
|
-$33.2M
|
-803,344
|
-39%
|
|
|
9
|
|
$49.1M
|
+$1.67M
|
+40,346
|
+4%
|
|
|
10
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$49M
|
+$14.8M
|
+358,119
|
+47%
|
|
|
11
|
Geode Capital Management
Boston,
Massachusetts
|
$39M
|
+$2.66M
|
+64,335
|
+8%
|
|
|
12
|
Dimensional Fund Advisors
Austin,
Texas
|
$37.7M
|
-$155K
|
-3,752
|
-0.4%
|
|
|
13
|
|
$35.6M
|
-$1.98M
|
-47,826
|
-6%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$30.4M
|
-$1.87M
|
-45,129
|
-6%
|
|
|
15
|
Bank of New York Mellon
New York
|
$25.8M
|
-$646K
|
-15,620
|
-3%
|
|
|
16
|
Candriam SCA
Strassen, Luxembourg,
Luxembourg
|
$22.5M
|
-$8.94M
|
-216,273
|
-30%
|
|
|
17
|
Eventide Asset Management
Boston,
Massachusetts
|
$22.1M
|
+$8.52M
|
+206,000
|
+69%
|
|
|
18
|
|
$21.4M
|
+$7.65M
|
+185,002
|
+61%
|
|
|
19
|
Principal Financial Group
Des Moines,
Iowa
|
$18.3M
|
-$369K
|
-8,917
|
-2%
|
|
|
20
|
Charles Schwab
San Francisco,
California
|
$16.4M
|
-$316K
|
-7,634
|
-2%
|
|
|
21
|
Baker Bros. Advisors
New York
|
$16.1M
|
-$1.69M
|
-40,772
|
-10%
|
|
|
22
|
|
$15.5M
|
+$6.39M
|
+154,439
|
+77%
|
|
|
23
|
Ameriprise
Minneapolis,
Minnesota
|
$12.7M
|
-$1.16M
|
-27,958
|
-9%
|
|
|
24
|
Panagora Asset Management
Boston,
Massachusetts
|
$11.5M
|
-$152K
|
-3,667
|
-1%
|
|
|
25
|
Rhenman & Partners Asset Management
Stockholm,
Sweden
|
$11.3M
|
-$27.3K
|
-659
|
-0.3%
|
|
