|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$189M
|
+$228K
|
+7,024
|
+0.1%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$107M
|
+$6.41M
|
+197,060
|
+7%
|
|
|
3
|
Vanguard Group
Malvern,
Pennsylvania
|
$55.9M
|
+$5.9M
|
+181,375
|
+12%
|
|
|
4
|
Polaris Venture Management Co IV
Boston,
Massachusetts
|
$50.3M
|
–
|
–
|
–
|
|
|
5
|
Oak Ridge Investments
Chicago,
Illinois
|
$45.6M
|
-$5.33M
|
-163,818
|
-11%
|
|
|
6
|
BlackRock Fund Advisors
San Francisco,
California
|
$38.3M
|
+$1.88M
|
+57,968
|
+5%
|
|
|
7
|
|
$27.2M
|
+$191K
|
+5,865
|
+0.7%
|
|
|
8
|
Granahan Investment Management
Waltham,
Massachusetts
|
$25.8M
|
+$1.21M
|
+37,150
|
+5%
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$25.2M
|
-$3.66M
|
-112,659
|
-13%
|
|
|
10
|
Pictet Asset Management (UK)
London,
United Kingdom
|
$24.9M
|
+$20.9M
|
+641,327
|
+745%
|
|
|
11
|
BlackRock Institutional Trust
San Francisco,
California
|
$24.8M
|
+$2.74M
|
+84,161
|
+13%
|
|
|
12
|
Eagle Asset Management
St Petersburg,
Florida
|
$24.6M
|
-$1.71M
|
-52,627
|
-7%
|
|
|
13
|
|
$23.9M
|
–
|
–
|
–
|
|
|
14
|
Novo Holdings A/S
Hellerup,
Denmark
|
$23.3M
|
+$416K
|
+12,800
|
+2%
|
|
|
15
|
BlackRock Advisors
Wilmington,
Delaware
|
$22.1M
|
-$855K
|
-26,292
|
-4%
|
|
|
16
|
Perceptive Advisors
New York
|
$20.5M
|
-$6.5M
|
-200,000
|
-25%
|
|
|
17
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$17.7M
|
-$29.7M
|
-914,941
|
-64%
|
|
|
18
|
Franklin Resources
San Mateo,
California
|
$16.8M
|
–
|
–
|
–
|
|
|
19
|
Westfield Capital Management
Boston,
Massachusetts
|
$16.8M
|
+$16.1M
|
+494,200
|
New
|
|
|
20
|
Eventide Asset Management
Boston,
Massachusetts
|
$14.6M
|
+$176K
|
+5,400
|
+1%
|
|
|
21
|
|
$14.2M
|
+$6.49M
|
+199,547
|
+92%
|
|
|
22
|
Credit Suisse
Zurich,
Switzerland
|
$13.2M
|
+$8.09M
|
+248,775
|
+177%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$12.7M
|
+$2.04M
|
+62,625
|
+20%
|
|
|
24
|
EcoR1 Capital
San Francisco,
California
|
$12.6M
|
+$3.29M
|
+101,092
|
+37%
|
|
|
25
|
Northern Trust
Chicago,
Illinois
|
$10.7M
|
+$868K
|
+26,701
|
+9%
|
|
