|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$144M
|
+$1.44M
|
+51,198
|
+1%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$97.8M
|
-$1.03M
|
-36,672
|
-1%
|
|
|
3
|
Polaris Venture Management Co IV
Boston,
Massachusetts
|
$84.8M
|
–
|
–
|
–
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$52.8M
|
+$6.39M
|
+226,740
|
+15%
|
|
|
5
|
|
$36.1M
|
+$1.1M
|
+39,200
|
+3%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$22.2M
|
+$1.37M
|
+48,799
|
+7%
|
|
|
7
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$22M
|
+$3.87M
|
+137,371
|
+23%
|
|
|
8
|
Franklin Resources
San Mateo,
California
|
$16.5M
|
-$3.18M
|
-112,800
|
-17%
|
|
|
9
|
|
$16.2M
|
+$1.59M
|
+56,578
|
+12%
|
|
|
10
|
Perceptive Advisors
New York
|
$13.5M
|
+$4.08M
|
+145,000
|
+48%
|
|
|
11
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$12.1M
|
-$299K
|
-10,611
|
-3%
|
|
|
12
|
Cormorant Asset Management
Boston,
Massachusetts
|
$12.1M
|
+$5.63M
|
+200,000
|
+100%
|
|
|
13
|
BlackRock Fund Advisors
San Francisco,
California
|
$10.7M
|
-$198K
|
-7,013
|
-2%
|
|
|
14
|
Citadel Advisors
Miami,
Florida
|
$10.4M
|
+$9.56M
|
+339,540
|
+5,783%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$6.51M
|
-$9.5M
|
-337,253
|
-61%
|
|
|
16
|
BlackRock Advisors
Wilmington,
Delaware
|
$6.43M
|
-$682K
|
-24,206
|
-10%
|
|
|
17
|
Deer VII & Co
Larchmont,
New York
|
$5.29M
|
–
|
–
|
–
|
|
|
18
|
BlackRock Institutional Trust
San Francisco,
California
|
$5.15M
|
-$330K
|
-11,725
|
-6%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$5.04M
|
+$1.85M
|
+65,699
|
+65%
|
|
|
20
|
|
$3.5M
|
-$144K
|
-5,100
|
-4%
|
|
|
21
|
Sphera Funds Management
Tel Aviv,
Israel
|
$3.02M
|
+$2.82M
|
+100,000
|
New
|
|
|
22
|
Driehaus Capital Management
Chicago,
Illinois
|
$3.01M
|
-$1.82M
|
-64,741
|
-39%
|
|
|
23
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$2.87M
|
+$1.01M
|
+35,894
|
+61%
|
|
|
24
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$2.59M
|
-$986K
|
-35,016
|
-29%
|
|
|
25
|
Wall Street Associates
Lajolla,
California
|
$2.52M
|
-$279K
|
-9,900
|
-11%
|
|