|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$160M
|
+$70.7M
|
+2,115,587
|
+81%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$111M
|
+$47.7M
|
+1,427,884
|
+77%
|
|
|
3
|
Polaris Venture Management Co IV
Boston,
Massachusetts
|
$95.2M
|
-$17.2M
|
-513,491
|
-15%
|
|
|
4
|
Adage Capital Partners
Boston,
Massachusetts
|
$51.7M
|
+$5.97M
|
+178,469
|
+13%
|
|
|
5
|
|
$39.2M
|
+$20M
|
+597,484
|
+107%
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$23.3M
|
+$10M
|
+299,820
|
+78%
|
|
|
7
|
Franklin Resources
San Mateo,
California
|
$22.3M
|
-$2.38M
|
-71,200
|
-10%
|
|
|
8
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$20M
|
+$19.7M
|
+589,053
|
New
|
|
|
9
|
State Street
Boston,
Massachusetts
|
$18.8M
|
+$14.9M
|
+444,966
|
+414%
|
|
|
10
|
|
$16.2M
|
-$925K
|
-27,648
|
-5%
|
|
|
11
|
Loomis, Sayles & Company
Boston,
Massachusetts
|
$14M
|
+$4.13M
|
+123,407
|
+43%
|
|
|
12
|
BlackRock Fund Advisors
San Francisco,
California
|
$12.3M
|
+$5.43M
|
+162,329
|
+81%
|
|
|
13
|
Perceptive Advisors
New York
|
$10.2M
|
+$10M
|
+300,000
|
New
|
|
|
14
|
|
$9.61M
|
+$1.39M
|
+41,527
|
+17%
|
|
|
15
|
BlackRock Advisors
Wilmington,
Delaware
|
$8.04M
|
+$262K
|
+7,824
|
+3%
|
|
|
16
|
Cormorant Asset Management
Boston,
Massachusetts
|
$6.79M
|
+$6.69M
|
+200,000
|
New
|
|
|
17
|
BlackRock Institutional Trust
San Francisco,
California
|
$6.19M
|
+$3.38M
|
+101,121
|
+125%
|
|
|
18
|
Deer VII & Co
Larchmont,
New York
|
$5.95M
|
-$31.1M
|
-930,889
|
-84%
|
|
|
19
|
|
$5.84M
|
-$56.7M
|
-1,696,000
|
-91%
|
|
|
20
|
Driehaus Capital Management
Chicago,
Illinois
|
$5.58M
|
+$1.35M
|
+40,281
|
+32%
|
|
|
21
|
|
$4.1M
|
+$1.88M
|
+56,200
|
+87%
|
|
|
22
|
Lord, Abbett & Co
Jersey City,
New Jersey
|
$4.1M
|
+$345K
|
+10,318
|
+9%
|
|
|
23
|
Iguana Healthcare Management
New York
|
$3.74M
|
+$3.68M
|
+110,000
|
New
|
|
|
24
|
Northern Trust
Chicago,
Illinois
|
$3.43M
|
+$480K
|
+14,346
|
+17%
|
|
|
25
|
Wall Street Associates
Lajolla,
California
|
$3.16M
|
+$10K
|
+300
|
+0.3%
|
|
