|
1
|
Fidelity Investments
Boston,
Massachusetts
|
$147M
|
+$16.6M
|
+572,176
|
+11%
|
|
|
2
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$77.8M
|
+$514K
|
+17,660
|
+0.6%
|
|
|
3
|
Oak Ridge Investments
Chicago,
Illinois
|
$39.7M
|
-$504K
|
-17,318
|
-1%
|
|
|
4
|
Polaris Venture Management Co IV
Boston,
Massachusetts
|
$39.1M
|
–
|
–
|
–
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$38.7M
|
+$5.83M
|
+200,473
|
+16%
|
|
|
6
|
Sectoral Asset Management
Montreal,
Quebec, Canada
|
$37.9M
|
+$9.19M
|
+315,971
|
+28%
|
|
|
7
|
BlackRock Fund Advisors
San Francisco,
California
|
$28.2M
|
+$4.34M
|
+149,193
|
+16%
|
|
|
8
|
State Street
Boston,
Massachusetts
|
$22.5M
|
+$9.78M
|
+336,459
|
+65%
|
|
|
9
|
Perceptive Advisors
New York
|
$21.2M
|
+$15.3M
|
+527,000
|
+191%
|
|
|
10
|
|
$20.9M
|
-$1.31M
|
-44,926
|
-5%
|
|
|
11
|
Eagle Asset Management
St Petersburg,
Florida
|
$20.5M
|
+$22.6M
|
+776,456
|
New
|
|
|
12
|
Granahan Investment Management
Waltham,
Massachusetts
|
$19.1M
|
+$1.92M
|
+66,078
|
+10%
|
|
|
13
|
|
$18.5M
|
+$1.81M
|
+62,110
|
+10%
|
|
|
14
|
BlackRock Advisors
Wilmington,
Delaware
|
$17.8M
|
+$4.84M
|
+166,393
|
+33%
|
|
|
15
|
Novo Holdings A/S
Hellerup,
Denmark
|
$17.8M
|
+$19.6M
|
+673,063
|
New
|
|
|
16
|
BlackRock Institutional Trust
San Francisco,
California
|
$17.1M
|
+$2.65M
|
+90,965
|
+16%
|
|
|
17
|
Franklin Resources
San Mateo,
California
|
$13.1M
|
-$12.3K
|
-423
|
-0.1%
|
|
|
18
|
Eventide Asset Management
Boston,
Massachusetts
|
$11.2M
|
+$8.72M
|
+300,000
|
+243%
|
|
|
19
|
Adage Capital Partners
Boston,
Massachusetts
|
$10.2M
|
–
|
–
|
–
|
|
|
20
|
Deerfield Management
New York
|
$9.33M
|
+$4.07M
|
+140,000
|
+66%
|
|
|
21
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$8.2M
|
+$4.14M
|
+142,447
|
+85%
|
|
|
22
|
Northern Trust
Chicago,
Illinois
|
$7.61M
|
+$1.04M
|
+35,763
|
+14%
|
|
|
23
|
Brown Advisory
Baltimore,
Maryland
|
$7.5M
|
+$24.3K
|
+835
|
+0.3%
|
|
|
24
|
EcoR1 Capital
San Francisco,
California
|
$7.13M
|
+$7.86M
|
+270,289
|
New
|
|
|
25
|
Geode Capital Management
Boston,
Massachusetts
|
$6.26M
|
+$727K
|
+25,003
|
+12%
|
|
