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Xenon Pharmaceuticals

246 hedge funds and large institutions have $3.78B invested in Xenon Pharmaceuticals in 2025 Q4 according to their latest regulatory filings, with 51 funds opening new positions, 81 increasing their positions, 74 reducing their positions, and 22 closing their positions.

New
Increased
Maintained
Reduced
Closed

132% more first-time investments, than exits

New positions opened: 51 | Existing positions closed: 22

12% more funds holding

Funds holding: 219246 (+27)

12% more capital invested

Capital invested by funds: $3.39B → $3.78B (+$399M)

9% more repeat investments, than reductions

Existing positions increased: 81 | Existing positions reduced: 74

0% more funds holding in top 10

Funds holding in top 10: 99 (0)

0.06% less ownership

Funds ownership: 109.36%109.29% (-0.06%)

34% less call options, than puts

Call options by funds: $36.4M | Put options by funds: $54.7M

Holders
246
Holders Change
+27
Holders Change %
+12.33%
% of All Funds
2.99%
Holding in Top 10
9
Holding in Top 10 Change
Holding in Top 10 Change %
% of All Funds
0.11%
New
51
Increased
81
Reduced
74
Closed
22
Calls
$36.4M
Puts
$54.7M
Net Calls
-$18.4M
Net Calls Change
-$14.5M
Name Holding Trade Value Shares
Change
Change in
Stake
BBA
51
Baker Bros. Advisors
New York
$16.6M
DTC
52
Deep Track Capital
Connecticut
$16.4M -$35M -833,565 -69%
SC
53
Stempoint Capital
New York
$15.6M +$6.56M +156,310 +81%
Morgan Stanley
54
Morgan Stanley
New York
$13.2M -$3.03M -72,240 -20%
DCM
55
DAFNA Capital Management
California
$12.9M
DnB Asset Management
56
DnB Asset Management
Norway
$12.2M +$997K +23,750 +10%
Two Sigma Advisers
57
Two Sigma Advisers
New York
$11.6M +$10.1M +241,220 +1,333%
Tudor Investment Corp
58
Tudor Investment Corp
Connecticut
$11.4M +$7.44M +177,178 +231%
NIP
59
Nicholas Investment Partners
California
$10.9M +$5.2M +123,891 +104%
ITP
60
Iron Triangle Partners
Connecticut
$10.5M +$9.81M +233,688 New
EP
61
Eversept Partners
New York
$10.4M +$9.72M +231,380 New
NFT
62
Nan Fung Trinity
Hong Kong
$10.2M +$2.87M +68,360 +43%
Bank of America
63
Bank of America
North Carolina
$9.92M +$935K +22,262 +11%
N
64
Nuveen
North Carolina
$9.69M -$338K -8,051 -4%
State of Wisconsin Investment Board
65
State of Wisconsin Investment Board
Wisconsin
$9.21M -$118K -2,803 -1%
ACM
66
ADAR1 Capital Management
Texas
$9.14M +$625K +14,871 +8%
PA
67
Perceptive Advisors
New York
$9M
Deutsche Bank
68
Deutsche Bank
Germany
$8.53M +$3.25M +77,282 +68%
Charles Schwab
69
Charles Schwab
California
$8.47M +$13.1K +312 +0.2%
New York State Common Retirement Fund
70
New York State Common Retirement Fund
New York
$8.37M +$630K +14,997 +9%
NCM
71
NEXTBio Capital Management
California
$8.23M +$7.72M +183,704 New
Neuberger Berman Group
72
Neuberger Berman Group
New York
$8.01M +$268K +6,393 +4%
PCM
73
Peregrine Capital Management
Minnesota
$7.84M +$7.34M +174,851 New
JG
74
Jain Global
New York
$7.79M -$3.3M -78,497 -31%
Marshall Wace
75
Marshall Wace
United Kingdom
$7.29M -$18.9M -449,431 -73%