|
1
|
RA Capital Management
Boston,
Massachusetts
|
$287M
|
–
|
–
|
–
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$85.9M
|
+$297K
|
+6,900
|
+0.3%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$63.6M
|
-$3.28M
|
-76,234
|
-4%
|
|
|
4
|
Boxer Capital
San Diego,
California
|
$60.8M
|
+$10.4M
|
+240,600
|
+18%
|
|
|
5
|
Janus Henderson Group
London,
|
$58.1M
|
+$6.91M
|
+160,545
|
+12%
|
|
|
6
|
|
$46M
|
+$14M
|
+324,659
|
+37%
|
|
|
7
|
BB Biotech
Schaffhausen,
Switzerland
|
$43.5M
|
+$10.4M
|
+241,789
|
+27%
|
|
|
8
|
Fidelity Investments
Boston,
Massachusetts
|
$39.7M
|
+$2.58M
|
+59,879
|
+6%
|
|
|
9
|
Bridger Management
New York
|
$21.5M
|
+$1.86M
|
+43,180
|
+8%
|
|
|
10
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$17.4M
|
+$2.85M
|
+66,280
|
+17%
|
|
|
11
|
New Leaf Venture Partners
New York
|
$16.6M
|
-$1.07M
|
-24,830
|
-5%
|
|
|
12
|
EcoR1 Capital
San Francisco,
California
|
$15.8M
|
-$45M
|
-1,046,201
|
-72%
|
|
|
13
|
Wells Fargo
San Francisco,
California
|
$13.8M
|
+$15.2M
|
+353,902
|
+5,258%
|
|
|
14
|
Point72 Asset Management
Stamford,
Connecticut
|
$13.4M
|
+$13.2M
|
+307,700
|
+727%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$13.1M
|
+$3.16M
|
+73,340
|
+27%
|
|
|
16
|
Eventide Asset Management
Boston,
Massachusetts
|
$12.5M
|
-$2.22M
|
-51,600
|
-14%
|
|
|
17
|
Vanguard Group
Malvern,
Pennsylvania
|
$11.2M
|
+$1.11M
|
+25,777
|
+10%
|
|
|
18
|
Perceptive Advisors
New York
|
$10.8M
|
-$7.75M
|
-180,000
|
-39%
|
|
|
19
|
Northern Trust
Chicago,
Illinois
|
$8.47M
|
+$2.92M
|
+67,774
|
+44%
|
|
|
20
|
Deerfield Management
New York
|
$6.84M
|
-$3.85M
|
-89,368
|
-33%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$6.46M
|
+$1.24M
|
+28,768
|
+21%
|
|
|
22
|
Berylson Capital Partners
Boston,
Massachusetts
|
$6.21M
|
–
|
–
|
–
|
|
|
23
|
Spark Investment Management
New York
|
$5.95M
|
+$1.85M
|
+42,900
|
+38%
|
|
|
24
|
|
$5.54M
|
+$6.24M
|
+144,942
|
New
|
|
|
25
|
|
$5.52M
|
-$504K
|
-11,707
|
-8%
|
|
