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Wave Life Sciences
WVE

Name Holding Trade Value Shares
Change 		Change in
Stake
RCM
1
RA Capital Management
Massachusetts
$147M – – –
Fidelity Investments
2
Fidelity Investments
Massachusetts
$38.5M -$1.75M -112,289 -6%
RG
3
Redmile Group
California
$22.7M -$2.22M -142,800 -12%
FCMI
4
Foresite Capital Management III
California
$20.1M -$6.88M -441,645 -31%
NLVP
5
New Leaf Venture Partners
New York
$16.2M – – –
PA
6
Perceptive Advisors
New York
$10.8M +$5.4M +346,595 +197%
CAM
7
Cormorant Asset Management
Massachusetts
$8.16M +$36.3K +2,328 +0.6%
EAM
8
Eventide Asset Management
Massachusetts
$7.86M +$5.92M +380,000 New
CCP
9
Clough Capital Partners
Massachusetts
$5.44M -$1.72M -110,200 -30%
BFA
10
BlackRock Fund Advisors
California
$3.99M +$2.98M +191,122 +11,640%
Vanguard Group
11
Vanguard Group
Pennsylvania
$2.44M +$238K +15,295 +15%
State Street
12
State Street
Massachusetts
$1.75M +$1.32M +84,798 New
Geode Capital Management
13
Geode Capital Management
Massachusetts
$1.24M +$298K +19,161 +47%
BIT
14
BlackRock Institutional Trust
California
$1.16M +$872K +55,960 New
Goldman Sachs
15
Goldman Sachs
New York
$931K +$512K +32,853 +270%
Renaissance Technologies
16
Renaissance Technologies
New York
$739K +$556K +35,700 New
Northern Trust
17
Northern Trust
Illinois
$690K +$328K +21,079 +172%
Deutsche Bank
18
Deutsche Bank
Germany
$687K +$518K +33,254 New
VIA
19
Vident Investment Advisory
Georgia
$669K +$504K +32,332 New
BIM
20
BlackRock Investment Management
Delaware
$579K +$436K +27,999 New
TCIM
21
TIAA CREF Investment Management
New York
$579K +$436K +28,000 New
Charles Schwab
22
Charles Schwab
California
$428K +$322K +20,656 New
Bank of New York Mellon
23
Bank of New York Mellon
New York
$385K +$290K +18,625 New
California State Teachers Retirement System (CalSTRS)
24
California State Teachers Retirement System (CalSTRS)
California
$321K +$242K +15,509 New
TA
25
Teachers Advisors
New York
$246K +$185K +11,898 New
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