|
1
|
RA Capital Management
Boston,
Massachusetts
|
$132M
|
–
|
–
|
–
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$41.4M
|
+$20.5M
|
+953,310
|
+75%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$32.7M
|
+$27.4M
|
+1,269,771
|
+261%
|
|
|
4
|
Fidelity Investments
Boston,
Massachusetts
|
$30.3M
|
-$3.59M
|
-166,400
|
-9%
|
|
|
5
|
Foresite Capital Management III
Larkspur,
California
|
$18.7M
|
+$7.07M
|
+327,972
|
+49%
|
|
|
6
|
Deerfield Management
New York
|
$13.9M
|
+$5.92M
|
+274,717
|
+58%
|
|
|
7
|
Perceptive Advisors
New York
|
$12.3M
|
-$51.7K
|
-2,400
|
-0.4%
|
|
|
8
|
New Leaf Venture Partners
New York
|
$12.2M
|
–
|
–
|
–
|
|
|
9
|
|
$10.2M
|
+$4.56M
|
+211,462
|
+63%
|
|
|
10
|
Eventide Asset Management
Boston,
Massachusetts
|
$8.06M
|
–
|
–
|
–
|
|
|
11
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$6.62M
|
+$7.67M
|
+355,835
|
New
|
|
|
12
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.01M
|
+$1.33M
|
+61,910
|
+40%
|
|
|
13
|
Cormorant Asset Management
Boston,
Massachusetts
|
$3.76M
|
-$6.03M
|
-280,000
|
-58%
|
|
|
14
|
Clough Capital Partners
Boston,
Massachusetts
|
$3.59M
|
-$4.64M
|
-215,103
|
-53%
|
|
|
15
|
Northern Trust
Chicago,
Illinois
|
$3.08M
|
+$1.42M
|
+66,120
|
+66%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$2.81M
|
+$684K
|
+31,743
|
+27%
|
|
|
17
|
Sabby Management
Miami Beach,
Florida
|
$2.64M
|
+$3.05M
|
+141,700
|
New
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$2.47M
|
+$1.22M
|
+56,506
|
+74%
|
|
|
19
|
Opaleye Management
Boston,
Massachusetts
|
$2.33M
|
+$1.01M
|
+46,700
|
+60%
|
|
|
20
|
Alyeska Investment Group
Chicago,
Illinois
|
$1.84M
|
+$2.13M
|
+98,801
|
New
|
|
|
21
|
Jennison Associates
New York
|
$1.4M
|
–
|
–
|
–
|
|
|
22
|
Emory University
Atlanta,
Georgia
|
$1.38M
|
+$10.3K
|
+477
|
+0.6%
|
|
|
23
|
Millennium Management
New York
|
$1.34M
|
+$1.56M
|
+72,189
|
New
|
|
|
24
|
Marshall Wace North America
New York
|
$1.16M
|
+$678K
|
+31,464
|
+106%
|
|
|
25
|
Iguana Healthcare Management
New York
|
$1.02M
|
+$1.19M
|
+55,000
|
New
|
|
