|
1
|
RA Capital Management
Boston,
Massachusetts
|
$301M
|
–
|
–
|
–
|
|
|
2
|
Redmile Group
San Francisco,
California
|
$89.7M
|
+$1.2M
|
+28,500
|
+1%
|
|
|
3
|
T. Rowe Price Associates
Baltimore,
Maryland
|
$69.7M
|
+$468K
|
+11,129
|
+0.6%
|
|
|
4
|
EcoR1 Capital
San Francisco,
California
|
$58.5M
|
+$22M
|
+522,909
|
+56%
|
|
|
5
|
Janus Henderson Group
London,
|
$54.5M
|
+$27.3M
|
+648,989
|
+92%
|
|
|
6
|
Boxer Capital
San Diego,
California
|
$54.1M
|
+$33.6M
|
+800,000
|
+145%
|
|
|
7
|
Fidelity Investments
Boston,
Massachusetts
|
$39.2M
|
-$5.53M
|
-131,650
|
-12%
|
|
|
8
|
BB Biotech
Schaffhausen,
Switzerland
|
$35.9M
|
+$1.68M
|
+40,000
|
+5%
|
|
|
9
|
|
$35.2M
|
-$2.43M
|
-57,737
|
-6%
|
|
|
10
|
Bridger Management
New York
|
$20.8M
|
+$7.63M
|
+181,486
|
+54%
|
|
|
11
|
Perceptive Advisors
New York
|
$18.6M
|
-$8.41M
|
-200,000
|
-30%
|
|
|
12
|
New Leaf Venture Partners
New York
|
$18.4M
|
–
|
–
|
–
|
|
|
13
|
ArrowMark Colorado Holdings
Denver,
Colorado
|
$15.6M
|
-$1.18M
|
-28,025
|
-7%
|
|
|
14
|
Eventide Asset Management
Boston,
Massachusetts
|
$15.2M
|
-$2.33M
|
-55,500
|
-13%
|
|
|
15
|
State Street
Boston,
Massachusetts
|
$10.8M
|
+$1.5M
|
+35,569
|
+15%
|
|
|
16
|
Deerfield Management
New York
|
$10.8M
|
-$1.95M
|
-46,500
|
-15%
|
|
|
17
|
Vanguard Group
Malvern,
Pennsylvania
|
$10.7M
|
+$228K
|
+5,424
|
+2%
|
|
|
18
|
Berylson Capital Partners
Boston,
Massachusetts
|
$6.51M
|
–
|
–
|
–
|
|
|
19
|
|
$6.25M
|
-$225K
|
-5,358
|
-3%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$6.17M
|
+$38.1K
|
+906
|
+0.6%
|
|
|
21
|
|
$6.01M
|
+$2.43M
|
+57,922
|
+63%
|
|
|
22
|
Geode Capital Management
Boston,
Massachusetts
|
$5.62M
|
+$288K
|
+6,857
|
+5%
|
|
|
23
|
Clough Capital Partners
Boston,
Massachusetts
|
$4.72M
|
-$1.75M
|
-41,600
|
-26%
|
|
|
24
|
Spark Investment Management
New York
|
$4.52M
|
+$3.05M
|
+72,500
|
+180%
|
|
|
25
|
Bank of New York Mellon
New York
|
$3.19M
|
+$935K
|
+22,244
|
+39%
|
|
