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Wave Life Sciences

176 hedge funds and large institutions have $903M invested in Wave Life Sciences in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 84 increasing their positions, 39 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,001% more call options, than puts

Call options by funds: $3.37M | Put options by funds: $306K

115% more repeat investments, than reductions

Existing positions increased: 84 | Existing positions reduced: 39

3.71% more ownership

Funds ownership: 85.6%89.31% (+3.7%)

10% less funds holding

Funds holding: 196176 (-20)

15% less capital invested

Capital invested by funds: $1.06B → $903M (-$159M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

43% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 40

Holders
176
Holders Change
-20
Holders Change %
-10.2%
% of All Funds
2.32%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
23
Increased
84
Reduced
39
Closed
40
Calls
$3.37M
Puts
$306K
Net Calls
+$3.06M
Net Calls Change
+$13K
Name Holding Trade Value Shares
Change
Change in
Stake
SCM
176
Silverarc Capital Management
Massachusetts
-$8.49M -1,050,374 Closed
TI
177
Trexquant Investment
Connecticut
-$1.81M -223,412 Closed
EI
178
EAM Investors
California
-$1.73M -213,848 Closed
Renaissance Technologies
179
Renaissance Technologies
New York
-$1.7M -210,220 Closed
Connor, Clark & Lunn Investment Management (CC&L)
180
Connor, Clark & Lunn Investment Management (CC&L)
British Columbia, Canada
-$1.02M -126,046 Closed
PCM
181
Prelude Capital Management
New York
-$883K -109,330 Closed
HSA
182
Hussman Strategic Advisors
Maryland
-$848K -105,000 Closed
AI
183
Atom Investors
Texas
-$798K -98,798 Closed
Tudor Investment Corp
184
Tudor Investment Corp
Connecticut
-$622K -76,926 Closed
ACM
185
Aquatic Capital Management
Illinois
-$580K -71,741 Closed
PP
186
PDT Partners
New York
-$452K -55,918 Closed
CF
187
Corebridge Financial
Texas
-$382K -47,299 Closed
CM
188
Caption Management
Oklahoma
-$287K -43,501 Closed
JF
189
Jump Financial
Illinois
-$337K -41,761 Closed
SPA
190
Sherbrooke Park Advisers
New York
-$318K -39,395 Closed
YIH
191
Y-Intercept (HK)
Hong Kong
-$288K -35,691 Closed
MS
192
Maven Securities
Jersey
-$283K -35,000 Closed
WIA
193
Wealthedge Investment Advisors
New York
-$239K -29,572 Closed
XT
194
XTX Topco
Cayman Islands
-$225K -27,792 Closed
PAMP
195
Polar Asset Management Partners
Ontario, Canada
-$221K -27,380 Closed
CM
196
Capula Management
Cayman Islands
-$214K -26,486 Closed
SC
197
SummitTX Capital
Texas
-$204K -25,249 Closed
MCM
198
Massar Capital Management
Connecticut
-$173K -21,356 Closed
AI
199
Allostery Investments
Connecticut
-$141K -17,500 Closed
AQR Capital Management
200
AQR Capital Management
Connecticut
-$130K -16,093 Closed

WVE Hedge Fund Activity: Q2 2025 in Review

176 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q2 2025, worth a combined $903M — down 15% from $1.06B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of WVE and 23 opened new positions — a net loss of 17 holders — while 39 trimmed existing stakes and 84 added.

The largest buyer was Adage Capital Partners, adding an estimated $16.5M. The largest seller was Fidelity Investments, cutting an estimated $10.1M.

  • 176 institutional investors held Wave Life Sciences (WVE) as of Q2 2025, down from 196 in Q1 2025.
  • Funds reported $903M of Wave Life Sciences stock for Q2 2025, down 15% quarter-over-quarter.
  • 23 funds opened new Wave Life Sciences positions in Q2 2025 and 40 closed out, a net change of -17 holders.
  • The largest Wave Life Sciences buyer in Q2 2025 was Adage Capital Partners, an estimated $16.5M added.
  • The largest Wave Life Sciences seller in Q2 2025 was Fidelity Investments, an estimated $10.1M sold.

Based on aggregated 13F filings for Q2 2025.