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Wave Life Sciences

189 hedge funds and large institutions have $1.05B invested in Wave Life Sciences in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 62 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

101% more call options, than puts

Call options by funds: $9.64M | Put options by funds: $4.79M

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more capital invested

Capital invested by funds: $903M → $1.05B (+$148M)

7% more funds holding

Funds holding: 176189 (+13)

0.97% more ownership

Funds ownership: 89.31%90.29% (+0.97%)

2% less repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 62

Holders
189
Holders Change
+13
Holders Change %
+7.39%
% of All Funds
2.48%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
32
Increased
61
Reduced
62
Closed
18
Calls
$9.64M
Puts
$4.79M
Net Calls
+$4.85M
Net Calls Change
+$1.79M
Name Holding Trade Value Shares
Change
Change in
Stake
PHK
151
Point72 Hong Kong
Hong Kong
$34.8K +$38.5K +4,753 New
GFM
152
GF Fund Management
China
$25.1K -$3.89K -481 -12%
AB
153
Amalgamated Bank
New York
$24K
TRCT
154
Tower Research Capital (TRC)
New York
$23.4K -$68.5K -8,461 -73%
AA
155
Ancora Advisors
Ohio
$22K
QCG
156
Quadrant Capital Group
Ohio
$17.5K +$19.4K +2,396 New
FDCDDQ
157
Federation des caisses Desjardins du Quebec
Quebec, Canada
$17.2K
Nisa Investment Advisors
158
Nisa Investment Advisors
Missouri
$11.5K
FFA
159
Farther Finance Advisors
California
$11.5K +$477 +59 +4%
WANY
160
Wealthspire Advisors (New York)
New York
$9.88K +$10.9K +1,350 New
SCM
161
Sterling Capital Management
North Carolina
$8.24K +$4.15K +513 +84%
Simplex Trading
162
Simplex Trading
Illinois
$8K -$364K -45,024 -97%
Walleye Trading
163
Walleye Trading
New York
$7.8K +$8.62K +1,065 New
Optiver Holding
164
Optiver Holding
Netherlands
$7.32K +$8.09K +1,000 New
Osaic Holdings
165
Osaic Holdings
Arizona
$7.29K -$8.71K -1,077 -52%
PD
166
Point72 (DIFC)
United Arab Emirates
$5.51K +$6.08K +752 New
MPWT
167
MassMutual Private Wealth & Trust
Connecticut
$5.33K +$3.15K +389 +115%
LFG
168
Larson Financial Group
Missouri
$5.07K -$5.96K -736 -52%
Daiwa Securities Group
169
Daiwa Securities Group
Japan
$4K
GI
170
GAMMA Investing
California
$3.23K -$607 -75 -15%
SPIA
171
Steward Partners Investment Advisory
New York
$2.93K -$6.47K -800 -67%
PNC Financial Services Group
172
PNC Financial Services Group
Pennsylvania
$2.36K +$510 +63 +24%
S
173
SignatureFD
Georgia
$2.27K
SAM
174
Smartleaf Asset Management
Massachusetts
$2.15K +$2.44K +301 New
RIL
175
Rothschild Investment LLC
Illinois
$1.79K -$445 -55 -18%

WVE Hedge Fund Activity: Q3 2025 in Review

189 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q3 2025, worth a combined $1.05B — up 16% from $903M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new WVE positions and 18 closed out — a net gain of 14 holders — while 61 added to existing stakes and 62 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $36.5M. The largest seller was T. Rowe Price Associates, cutting an estimated $9.27M.

  • 189 institutional investors held Wave Life Sciences (WVE) as of Q3 2025, up from 176 in Q2 2025.
  • Funds reported $1.05B of Wave Life Sciences stock for Q3 2025, up 16% quarter-over-quarter.
  • 32 funds opened new Wave Life Sciences positions in Q3 2025 and 18 closed out, a net change of +14 holders.
  • The largest Wave Life Sciences buyer in Q3 2025 was Fidelity Investments, an estimated $36.5M added.
  • The largest Wave Life Sciences seller in Q3 2025 was T. Rowe Price Associates, an estimated $9.27M sold.

Based on aggregated 13F filings for Q3 2025.