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Wave Life Sciences

176 hedge funds and large institutions have $903M invested in Wave Life Sciences in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 84 increasing their positions, 39 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,001% more call options, than puts

Call options by funds: $3.37M | Put options by funds: $306K

115% more repeat investments, than reductions

Existing positions increased: 84 | Existing positions reduced: 39

3.71% more ownership

Funds ownership: 85.6%89.31% (+3.7%)

10% less funds holding

Funds holding: 196176 (-20)

15% less capital invested

Capital invested by funds: $1.06B → $903M (-$159M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

43% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 40

Holders
176
Holders Change
-20
Holders Change %
-10.2%
% of All Funds
2.32%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
23
Increased
84
Reduced
39
Closed
40
Calls
$3.37M
Puts
$306K
Net Calls
+$3.06M
Net Calls Change
+$13K
Name Holding Trade Value Shares
Change
Change in
Stake
Pictet Asset Management
126
Pictet Asset Management
Switzerland
$107K +$27.1K +4,102 +33%
CPIG
127
Chicago Partners Investment Group
Illinois
$105K -$2.92K -443 -3%
VCIM
128
Velan Capital Investment Management
Georgia
$97.5K +$13.2K +2,000 +15%
Nomura Holdings
129
Nomura Holdings
Japan
$96.4K -$918 -139 -0.9%
Victory Capital Management
130
Victory Capital Management
Texas
$95.4K -$958 -145 -1%
CWM
131
CIBC World Markets
New York
$89.8K -$50.3K -7,612 -36%
Rafferty Asset Management
132
Rafferty Asset Management
New York
$87.6K +$2.06K +312 +2%
VIA
133
Virtus Investment Advisers
Connecticut
$84.9K +$7.99K +1,210 +10%
Prudential Financial
134
Prudential Financial
New Jersey
$80.1K +$81.4K +12,320 New
NSEDCP
135
NJ State Employees Deferred Compensation Plan
New Jersey
$76K
TRCT
136
Tower Research Capital (TRC)
New York
$75.8K +$23.8K +3,609 +45%
Creative Planning
137
Creative Planning
Kansas
$74.6K +$5.69K +861 +8%
AIP
138
Ameritas Investment Partners
Nebraska
$74.4K +$11.9K +1,802 +19%
MC
139
Matisse Capital
Oregon
$72.8K -$9.51K -1,440 -11%
ECM
140
ExodusPoint Capital Management
New York
$67K -$568K -86,004 -89%
SO
141
STRS Ohio
Ohio
$52K -$279K -42,300 -84%
US Bancorp
142
US Bancorp
Minnesota
$47.6K
Mirae Asset Global Investments
143
Mirae Asset Global Investments
South Korea
$38.7K +$6.86K +1,039 +21%
GFM
144
GF Fund Management
China
$25.4K
Group One Trading
145
Group One Trading
Illinois
$24.6K -$106K -16,111 -81%
AB
146
Amalgamated Bank
New York
$22K
AA
147
Ancora Advisors
Ohio
$19.5K
FDCDDQ
148
Federation des caisses Desjardins du Quebec
Quebec, Canada
$15.3K +$9.91K +1,500 +176%
Osaic Holdings
149
Osaic Holdings
Arizona
$13.4K +$12.8K +1,939 +1,629%
Nisa Investment Advisors
150
Nisa Investment Advisors
Missouri
$10.2K +$8.12K +1,230 +355%

WVE Hedge Fund Activity: Q2 2025 in Review

176 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q2 2025, worth a combined $903M — down 15% from $1.06B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of WVE and 23 opened new positions — a net loss of 17 holders — while 39 trimmed existing stakes and 84 added.

The largest buyer was Adage Capital Partners, adding an estimated $16.5M. The largest seller was Fidelity Investments, cutting an estimated $10.1M.

  • 176 institutional investors held Wave Life Sciences (WVE) as of Q2 2025, down from 196 in Q1 2025.
  • Funds reported $903M of Wave Life Sciences stock for Q2 2025, down 15% quarter-over-quarter.
  • 23 funds opened new Wave Life Sciences positions in Q2 2025 and 40 closed out, a net change of -17 holders.
  • The largest Wave Life Sciences buyer in Q2 2025 was Adage Capital Partners, an estimated $16.5M added.
  • The largest Wave Life Sciences seller in Q2 2025 was Fidelity Investments, an estimated $10.1M sold.

Based on aggregated 13F filings for Q2 2025.