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Wave Life Sciences

176 hedge funds and large institutions have $903M invested in Wave Life Sciences in 2025 Q2 according to their latest regulatory filings, with 23 funds opening new positions, 84 increasing their positions, 39 reducing their positions, and 40 closing their positions.

New
Increased
Maintained
Reduced
Closed

1,001% more call options, than puts

Call options by funds: $3.37M | Put options by funds: $306K

115% more repeat investments, than reductions

Existing positions increased: 84 | Existing positions reduced: 39

3.71% more ownership

Funds ownership: 85.6%89.31% (+3.7%)

10% less funds holding

Funds holding: 196176 (-20)

15% less capital invested

Capital invested by funds: $1.06B → $903M (-$159M)

25% less funds holding in top 10

Funds holding in top 10: 43 (-1)

43% less first-time investments, than exits

New positions opened: 23 | Existing positions closed: 40

Holders
176
Holders Change
-20
Holders Change %
-10.2%
% of All Funds
2.32%
Holding in Top 10
3
Holding in Top 10 Change
-1
Holding in Top 10 Change %
-25%
% of All Funds
0.04%
New
23
Increased
84
Reduced
39
Closed
40
Calls
$3.37M
Puts
$306K
Net Calls
+$3.06M
Net Calls Change
+$13K
Name Holding Trade Value Shares
Change
Change in
Stake
BC
101
Birchview Capital
Vermont
$262K
DMKJ
102
David M. Knott Jr
$260K +$198K +30,000 +300%
Envestnet Asset Management
103
Envestnet Asset Management
Illinois
$240K +$5.21K +789 +2%
Mitsubishi UFJ Asset Management
104
Mitsubishi UFJ Asset Management
Japan
$235K +$115K +17,424 +93%
SFI
105
Susquehanna Fundamental Investments
Pennsylvania
$235K -$377K -57,134 -61%
HS
106
HighVista Strategies
Massachusetts
$234K -$115K -17,416 -33%
NRD
107
Nebula Research & Development
New York
$223K +$18.1K +2,748 +9%
KCM
108
Kennedy Capital Management
Missouri
$221K +$225K +34,000 New
Citadel Advisors
109
Citadel Advisors
Florida
$211K -$195K -29,551 -48%
ASRS
110
Arizona State Retirement System
Arizona
$204K +$19.4K +2,943 +10%
VOYA Investment Management
111
VOYA Investment Management
Georgia
$200K -$294K -44,525 -59%
MAM
112
Martingale Asset Management
Massachusetts
$198K -$35K -5,300 -15%
Teacher Retirement System of Texas
113
Teacher Retirement System of Texas
Texas
$188K +$14.6K +2,206 +8%
ProShare Advisors
114
ProShare Advisors
Maryland
$187K +$6.33K +959 +3%
Royal Bank of Canada
115
Royal Bank of Canada
Ontario, Canada
$175K +$170K +25,709 +2,283%
AG
116
Algert Global
California
$172K +$174K +26,420 New
PFSRSONJ
117
Police & Firemen's Retirement System of New Jersey
New Jersey
$168K +$33.3K +5,041 +24%
Marshall Wace
118
Marshall Wace
United Kingdom
$161K +$164K +24,828 New
BCI
119
Brinker Capital Investments
Pennsylvania
$159K +$34.2K +5,182 +27%
PA
120
Profund Advisors
Maryland
$146K -$70.9K -10,738 -32%
KK
121
KLP Kapitalforvaltning
Norway
$135K
KIA
122
Kraematon Investment Advisors
Massachusetts
$126K +$3.14K +475 +3%
I
123
InceptionR
California
$115K +$116K +17,617 New
State Board of Administration of Florida Retirement System
124
State Board of Administration of Florida Retirement System
Florida
$110K
Raymond James Financial
125
Raymond James Financial
Florida
$109K +$7.15K +1,083 +7%

WVE Hedge Fund Activity: Q2 2025 in Review

176 of the 7,595 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q2 2025, worth a combined $903M — down 15% from $1.06B a quarter earlier.

Sellers outnumbered buyers: 40 funds closed out of WVE and 23 opened new positions — a net loss of 17 holders — while 39 trimmed existing stakes and 84 added.

The largest buyer was Adage Capital Partners, adding an estimated $16.5M. The largest seller was Fidelity Investments, cutting an estimated $10.1M.

  • 176 institutional investors held Wave Life Sciences (WVE) as of Q2 2025, down from 196 in Q1 2025.
  • Funds reported $903M of Wave Life Sciences stock for Q2 2025, down 15% quarter-over-quarter.
  • 23 funds opened new Wave Life Sciences positions in Q2 2025 and 40 closed out, a net change of -17 holders.
  • The largest Wave Life Sciences buyer in Q2 2025 was Adage Capital Partners, an estimated $16.5M added.
  • The largest Wave Life Sciences seller in Q2 2025 was Fidelity Investments, an estimated $10.1M sold.

Based on aggregated 13F filings for Q2 2025.