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Wave Life Sciences

218 hedge funds and large institutions have $3.11B invested in Wave Life Sciences in 2025 Q4 according to their latest regulatory filings, with 73 funds opening new positions, 78 increasing their positions, 47 reducing their positions, and 39 closing their positions.

New
Increased
Maintained
Reduced
Closed

195% more capital invested

Capital invested by funds: $1.05B → $3.11B (+$2.06B)

100% more funds holding in top 10

Funds holding in top 10: 48 (+4)

87% more first-time investments, than exits

New positions opened: 73 | Existing positions closed: 39

66% more repeat investments, than reductions

Existing positions increased: 78 | Existing positions reduced: 47

18.99% more ownership

Funds ownership: 90.29%109.27% (+19%)

16% more call options, than puts

Call options by funds: $50M | Put options by funds: $42.9M

15% more funds holding

Funds holding: 189218 (+29)

Holders
218
Holders Change
+29
Holders Change %
+15.34%
% of All Funds
2.65%
Holding in Top 10
8
Holding in Top 10 Change
+4
Holding in Top 10 Change %
+100%
% of All Funds
0.1%
New
73
Increased
78
Reduced
47
Closed
39
Calls
$50M
Puts
$42.9M
Net Calls
+$7.04M
Net Calls Change
+$2.19M
Name Holding Trade Value Shares
Change
Change in
Stake
PFM
76
Privium Fund Management
Netherlands
$3.28M +$234K +23,010 +14%
Manulife (Manufacturers Life Insurance)
77
Manulife (Manufacturers Life Insurance)
Ontario, Canada
$3.13M +$583K +57,369 +46%
Bank of America
78
Bank of America
North Carolina
$3.11M -$4.9M -482,295 -73%
Invesco
79
Invesco
Georgia
$3.06M +$394K +38,806 +27%
SCM
80
Squadron Capital Management
Illinois
$2.98M +$1.78M +175,000 New
DFO
81
Duquesne Family Office
New York
$2.94M +$1.76M +173,000 New
Principal Financial Group
82
Principal Financial Group
Iowa
$2.89M +$1.73M +170,170 New
UBS AM
83
UBS AM
Illinois
$2.8M +$1.68M +164,985 New
SI
84
Sofinnova Investments
California
$2.69M -$130K -12,761 -7%
BGM
85
Burkehill Global Management
New York
$2.55M +$1.52M +150,000 New
RhumbLine Advisers
86
RhumbLine Advisers
Massachusetts
$2.41M -$176K -17,278 -11%
Mirae Asset Global ETFs Holdings
87
Mirae Asset Global ETFs Holdings
Hong Kong
$2.29M +$2.87K +282 +0.2%
AG
88
Algert Global
California
$2.08M +$1.24M +122,470 New
VOYA Investment Management
89
VOYA Investment Management
Georgia
$1.92M -$1.47M -145,136 -56%
AllianceBernstein
90
AllianceBernstein
Tennessee
$1.9M +$195K +19,200 +21%
Raymond James Financial
91
Raymond James Financial
Florida
$1.89M +$970K +95,483 +609%
Jane Street
92
Jane Street
New York
$1.89M -$5.17M -508,717 -82%
California State Teachers Retirement System (CalSTRS)
93
California State Teachers Retirement System (CalSTRS)
California
$1.83M +$93.3K +9,185 +9%
JJBC
94
James J. Burns & Company
New York
$1.8M
IUHSA
95
Itau Unibanco Holding S.A.
Brazil
$1.75M +$1.04M +102,000 New
LP
96
LMR Partners
United Kingdom
$1.7M +$1.02M +100,000 New
SGM
97
Seven Grand Managers
New York
$1.7M +$1.02M +100,000 New
Deutsche Bank
98
Deutsche Bank
Germany
$1.63M +$14.6K +1,441 +2%
DFCM
99
Dark Forest Capital Management
Puerto Rico
$1.62M -$1.7M -167,509 -64%
Legal & General Group
100
Legal & General Group
United Kingdom
$1.6M -$80.6K -7,931 -8%