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Wave Life Sciences

189 hedge funds and large institutions have $1.05B invested in Wave Life Sciences in 2025 Q3 according to their latest regulatory filings, with 32 funds opening new positions, 61 increasing their positions, 62 reducing their positions, and 18 closing their positions.

New
Increased
Maintained
Reduced
Closed

101% more call options, than puts

Call options by funds: $9.64M | Put options by funds: $4.79M

78% more first-time investments, than exits

New positions opened: 32 | Existing positions closed: 18

33% more funds holding in top 10

Funds holding in top 10: 34 (+1)

16% more capital invested

Capital invested by funds: $903M → $1.05B (+$148M)

7% more funds holding

Funds holding: 176189 (+13)

0.97% more ownership

Funds ownership: 89.31%90.29% (+0.97%)

2% less repeat investments, than reductions

Existing positions increased: 61 | Existing positions reduced: 62

Holders
189
Holders Change
+13
Holders Change %
+7.39%
% of All Funds
2.48%
Holding in Top 10
4
Holding in Top 10 Change
+1
Holding in Top 10 Change %
+33.33%
% of All Funds
0.05%
New
32
Increased
61
Reduced
62
Closed
18
Calls
$9.64M
Puts
$4.79M
Net Calls
+$4.85M
Net Calls Change
+$1.79M
Name Holding Trade Value Shares
Change
Change in
Stake
JJBC
76
James J. Burns & Company
New York
$774K -$130K -16,111 -13%
Legal & General Group
77
Legal & General Group
United Kingdom
$746K -$1.08K -134 -0.1%
California State Teachers Retirement System (CalSTRS)
78
California State Teachers Retirement System (CalSTRS)
California
$721K +$2.09K +258 +0.3%
IC
79
Ikarian Capital
Texas
$702K -$527K -65,182 -40%
Deutsche Bank
80
Deutsche Bank
Germany
$690K +$78.8K +9,734 +12%
ECM
81
ExodusPoint Capital Management
New York
$689K +$678K +83,816 +817%
AllianceBernstein
82
AllianceBernstein
Tennessee
$680K
DMKJ
83
David M. Knott Jr
$659K +$405K +50,000 +125%
Macquarie Group
84
Macquarie Group
Australia
$600K -$1.5M -184,901 -69%
CUAMC
85
China Universal Asset Management Company
China
$570K -$125K -15,475 -17%
APM
86
a16z Perennial Management
California
$568K
Wells Fargo
87
Wells Fargo
California
$540K -$411K -50,856 -41%
SEI Investments
88
SEI Investments
Pennsylvania
$529K -$134K -16,564 -19%
TC
89
TwinBeech Capital
New York
$476K -$798K -98,654 -60%
Franklin Resources
90
Franklin Resources
California
$456K +$2.24K +277 +0.4%
HS
91
HighVista Strategies
Massachusetts
$434K +$189K +23,303 +65%
MIM
92
MetLife Investment Management
New Jersey
$433K -$65.1K -8,051 -12%
State of Wisconsin Investment Board
93
State of Wisconsin Investment Board
Wisconsin
$433K +$111K +13,673 +30%
SC
94
SummitTX Capital
Texas
$392K +$434K +53,611 New
Zurich Cantonal Bank
95
Zurich Cantonal Bank
Switzerland
$381K -$2.08K -257 -0.5%
Janus Henderson Group
96
Janus Henderson Group
United Kingdom
$379K
GCP
97
GSA Capital Partners
United Kingdom
$375K +$414K +51,198 New
Handelsbanken Fonder
98
Handelsbanken Fonder
Sweden
$372K
SFM
99
Sphera Funds Management
Israel
$366K +$405K +50,000 New
IIM
100
INTECH Investment Management
Florida
$336K -$164K -20,306 -31%

WVE Hedge Fund Activity: Q3 2025 in Review

189 of the 7,620 institutional investors tracked by Wall St. Rank reported a position in Wave Life Sciences (WVE) for Q3 2025, worth a combined $1.05B — up 16% from $903M a quarter earlier.

Buyers outnumbered sellers: 32 funds opened new WVE positions and 18 closed out — a net gain of 14 holders — while 61 added to existing stakes and 62 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $36.5M. The largest seller was T. Rowe Price Associates, cutting an estimated $9.27M.

  • 189 institutional investors held Wave Life Sciences (WVE) as of Q3 2025, up from 176 in Q2 2025.
  • Funds reported $1.05B of Wave Life Sciences stock for Q3 2025, up 16% quarter-over-quarter.
  • 32 funds opened new Wave Life Sciences positions in Q3 2025 and 18 closed out, a net change of +14 holders.
  • The largest Wave Life Sciences buyer in Q3 2025 was Fidelity Investments, an estimated $36.5M added.
  • The largest Wave Life Sciences seller in Q3 2025 was T. Rowe Price Associates, an estimated $9.27M sold.

Based on aggregated 13F filings for Q3 2025.