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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 145 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.58%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
145
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
CAM
1051
Cozad Asset Management
Illinois
$401K – – –
Two Sigma Advisers
1052
Two Sigma Advisers
New York
$401K +$401K +900 New
YIA
1053
YHB Investment Advisors
Connecticut
$397K -$22.3K -50 -5%
AMCA
1054
Arthur M. Cohen & Associates
Illinois
$396K – – –
PFBT
1055
Parkside Financial Bank & Trust
Missouri
$394K – – –
FWM
1056
Forza Wealth Management
Florida
$392K – – –
WANY
1057
Wealthspire Advisors (New York)
New York
$392K +$67.2K +151 +21%
PDL
1058
Portfolio Design Labs
California
$392K -$381K -856 -49%
EI
1059
Ellevest Inc
New York
$390K -$103K -231 -21%
GKFF
1060
George Kaiser Family Foundation
Oklahoma
$387K +$121K +272 +46%
PGCM
1061
Prescott Group Capital Management
Oklahoma
$387K +$121K +272 +46%
PWPS
1062
Pinnacle Wealth Planning Services
Ohio
$386K -$97.1K -218 -20%
DWA
1063
Douglass Winthrop Advisors
New York
$386K – – –
LFG
1064
Lockerman Financial Group
California
$384K +$6.68K +15 +2%
SIM
1065
Sentry Investment Management
Wisconsin
$383K – – –
FB
1066
Fulton Bank
Pennsylvania
$377K +$122K +274 +48%
BFS
1067
BridgePort Financial Solutions
Iowa
$375K +$22.3K +50 +6%
AA
1068
Ancora Advisors
Ohio
$372K -$891 -2 -0.2%
BMCM
1069
Bryn Mawr Capital Management
Pennsylvania
$368K +$165K +370 +81%
OC
1070
Opinicus Capital
Florida
$366K +$1.34K +3 +0.4%
FFA
1071
Founders Financial Alliance
North Carolina
$365K -$21.8K -49 -6%
LA
1072
LVW Advisors
New York
$362K +$8.46K +19 +2%
LFG
1073
Larson Financial Group
Missouri
$361K -$11.1K -25 -3%
SYBT
1074
Stock Yards Bank & Trust
Kentucky
$360K +$131K +295 +57%
OWCM
1075
One Wealth Capital Management
Arizona
$357K +$9.35K +21 +3%
41 42
43
44 45