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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 145 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.58%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
145
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
PCH
976
PGIM Custom Harvest
New Jersey
$543K -$10.7K -24 -2%
Holocene Advisors
977
Holocene Advisors
New York
$541K – – –
WH
978
Willner & Heller
California
$541K +$26.7K +60 +5%
GVAG
979
Great Valley Advisor Group
Delaware
$539K -$4.62M -10,372 -90%
CPIG
980
Chicago Partners Investment Group
Illinois
$536K +$83.9K +176 +19%
FCFC
981
First Commonwealth Financial Corp
Pennsylvania
$535K – – –
GITFIT
982
Generali Investments Towarzystwo Funduszy Inwestycyjnych (TFI)
Poland
$534K – – –
AWE
983
Avidian Wealth Enterprises
Texas
$531K -$14.7K -33 -3%
KIM
984
Kestra Investment Management
Texas
$529K +$251K +538 +90%
CFP
985
Catalyst Financial Partners
Massachusetts
$521K -$85K -191 -14%
FFS
986
Founders Financial Securities
Maryland
$514K -$5.34K -12 -1%
BA
987
Bridgewater Advisors
New York
$514K -$7.5K -16 -1%
LCM
988
LCM Capital Management
Illinois
$511K +$1.78K +4 +0.3%
KFS
989
Keynote Financial Services
Connecticut
$510K +$17.8K +40 +4%
PCS
990
Personal CFO Solutions
New Jersey
$506K -$9.79K -22 -2%
OFS
991
Orrstown Financial Services
Pennsylvania
$506K +$71.2K +160 +16%
RMDI
992
R.M. Davis Inc
Maine
$505K +$1.78K +4 +0.4%
WJWM
993
Williams Jones Wealth Management
New York
$505K – – –
NAS
994
Nicolet Advisory Services
Wisconsin
$501K +$68.4K +148 +16%
AWM
995
Accurate Wealth Management
Florida
$500K -$185K -385 -27%
GFP
996
Gryphon Financial Partners
Ohio
$500K +$2.23K +5 +0.4%
AFG
997
Albion Financial Group
Utah
$496K – – –
BCP
998
Blue Chip Partners
Michigan
$492K +$118K +265 +32%
ILI
999
Invesco LLC (Illinois)
Illinois
$486K – – –
DBRC
1000
D.B. Root & Company
Pennsylvania
$482K -$12K -27 -2%
38 39
40
41 42