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Vertex Pharmaceuticals

1,747 hedge funds and large institutions have $119B invested in Vertex Pharmaceuticals in 2026 Q2 according to their latest regulatory filings, with 191 funds opening new positions, 704 increasing their positions, 616 reducing their positions, and 109 closing their positions.

New
Increased
Maintained
Reduced
Closed

75% more first-time investments, than exits

New positions opened: 191 | Existing positions closed: 109

14% more repeat investments, than reductions

Existing positions increased: 704 | Existing positions reduced: 616

13% more capital invested

Capital invested by funds: $106B → $119B (+$13.4B)

3% more funds holding

Funds holding: 1,6951,747 (+52)

1.38% more ownership

Funds ownership: 93.56%94.94% (+1.4%)

9% more call options, than puts

Call options by funds: $853M | Put options by funds: $783M

29% less funds holding in top 10

Funds holding in top 10: 1712 (-5)

Holders
1,747
Holders Change
+52
Holders Change %
+3.07%
% of All Funds
21.1%
Holding in Top 10
12
Holding in Top 10 Change
-5
Holding in Top 10 Change %
-29.41%
% of All Funds
0.14%
New
191
Increased
704
Reduced
616
Closed
109
Calls
$853M
Puts
$783M
Net Calls
+$69.7M
Net Calls Change
-$97.3M
Name Holding Trade Value Shares
Change
Change in
Stake
Hudson Bay Capital Management
76
Hudson Bay Capital Management
Connecticut
$194M +$153M +345,440 +768%
Principal Financial Group
77
Principal Financial Group
Iowa
$193M -$16.4M -37,012 -9%
Zurich Cantonal Bank
78
Zurich Cantonal Bank
Switzerland
$189M +$1.66M +3,749 +1%
DZ Bank
79
DZ Bank
Germany
$178M -$2.3M -5,181 -1%
Canada Pension Plan Investment Board
80
Canada Pension Plan Investment Board
Ontario, Canada
$176M +$73.1M +165,031 +87%
Russell Investments Group
81
Russell Investments Group
United Kingdom
$168M -$13.6M -30,701 -8%
Universal-Beteiligungs- und Servicegesellschaft
82
Universal-Beteiligungs- und Servicegesellschaft
Germany
$161M -$6.47M -14,595 -4%
Renaissance Technologies
83
Renaissance Technologies
New York
$159M -$45.1M -101,680 -24%
Bank Julius Baer & Co
84
Bank Julius Baer & Co
Switzerland
$159M +$871K +1,965 +0.6%
AT
85
AMF Tjänstepension
Sweden
$156M +$819K +1,848 +0.6%
First Trust Advisors
86
First Trust Advisors
Illinois
$144M -$7.66M -17,282 -6%
LPL Financial
87
LPL Financial
California
$144M +$9.33M +21,049 +8%
ProShare Advisors
88
ProShare Advisors
Maryland
$143M -$38M -85,685 -23%
Two Sigma Investments
89
Two Sigma Investments
New York
$142M -$41.3M -93,146 -25%
Swedbank
90
Swedbank
Sweden
$140M +$4.83M +10,891 +4%
New York State Common Retirement Fund
91
New York State Common Retirement Fund
New York
$138M -$6.56M -14,800 -5%
Baillie Gifford & Co
92
Baillie Gifford & Co
United Kingdom
$135M +$32.4M +73,140 +37%
BNP Paribas Financial Markets
93
BNP Paribas Financial Markets
France
$130M -$68M -153,367 -37%
Cerity Partners
94
Cerity Partners
New York
$127M -$18.1M -40,780 -14%
Public Employees Retirement Association of Colorado
95
Public Employees Retirement Association of Colorado
Colorado
$124M -$27.3M -61,561 -20%
NAS
96
Nykredit A/S
Denmark
$123M +$110M +248,068 New
Royal London Asset Management
97
Royal London Asset Management
United Kingdom
$120M -$4.84M -10,912 -4%
BMSSC
98
B. Metzler seel. Sohn & Co
Germany
$115M -$124M -279,655 -55%
Aviva
99
Aviva
United Kingdom
$111M +$506K +1,141 +0.5%
IG
100
ING Group
Netherlands
$111M +$69.9M +157,699 +241%

VRTX Hedge Fund Activity: Q2 2026 in Review

1,747 of the 8,279 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q2 2026, worth a combined $119B — up 13% from $106B a quarter earlier.

Buyers outnumbered sellers: 191 funds opened new VRTX positions and 109 closed out — a net gain of 82 holders — while 704 added to existing stakes and 616 trimmed.

The largest buyer was Franklin Resources, adding an estimated $1.24B. The largest seller was Capital Research Global Investors, cutting an estimated $725M.

  • 1,747 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q2 2026, up from 1,695 in Q1 2026.
  • Funds reported $119B of Vertex Pharmaceuticals stock for Q2 2026, up 13% quarter-over-quarter.
  • 191 funds opened new Vertex Pharmaceuticals positions in Q2 2026 and 109 closed out, a net change of +82 holders.
  • The largest Vertex Pharmaceuticals buyer in Q2 2026 was Franklin Resources, an estimated $1.24B added.
  • The largest Vertex Pharmaceuticals seller in Q2 2026 was Capital Research Global Investors, an estimated $725M sold.

Based on aggregated 13F filings for Q2 2026.