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Vertex Pharmaceuticals
VRTX

Overview Fund Activity

1,536 hedge funds and large institutions have $107B invested in Vertex Pharmaceuticals in 2025 Q2 according to their latest regulatory filings, with 117 funds opening new positions, 606 increasing their positions, 605 reducing their positions, and 145 closing their positions.

New
Increased
Maintained
Reduced
Closed
Holders
1,536
Holders Change
-59
Holders Change %
-3.7%
% of All Funds
20.58%
Holding in Top 10
16
Holding in Top 10 Change
-10
Holding in Top 10 Change %
-38.46%
% of All Funds
0.21%
New
117
Increased
606
Reduced
605
Closed
145
Calls
$930M
Puts
$554M
Net Calls
+$376M
Net Calls Change
+$202M

Top Buyers

1
Capital International Investors
Capital International Investors
California
+$884M
2
Victory Capital Management
Victory Capital Management
Texas
+$836M
3
Capital Research Global Investors
Capital Research Global Investors
California
+$700M
4
Jennison Associates
Jennison Associates
New York
+$485M
5
UBS AM
UBS AM
Illinois
+$226M

Top Sellers

1
Amundi
Amundi
France
-$898M
2
JPMorgan Chase & Co
JPMorgan Chase & Co
New York
-$840M
3
Fidelity Investments
Fidelity Investments
Massachusetts
-$588M
4
Massachusetts Financial Services
Massachusetts Financial Services
Massachusetts
-$330M
5
Wellington Management Group
Wellington Management Group
Massachusetts
-$286M
Name Holding Trade Value Shares
Change 		Shares
Change %
Legal & General Group
26
Legal & General Group
United Kingdom
$841M -$1.96M -4,392 -0.2%
Charles Schwab
27
Charles Schwab
California
$790M +$21.5M +48,344 +3%
Parnassus Investments
28
Parnassus Investments
California
$762M -$27.3M -61,278 -3%
Bank of New York Mellon
29
Bank of New York Mellon
New York
$713M -$49.5M -111,192 -6%
ClearBridge Investments
30
ClearBridge Investments
New York
$680M -$67.4M -151,307 -9%
Deutsche Bank
31
Deutsche Bank
Germany
$627M +$27M +60,748 +5%
Royal Bank of Canada
32
Royal Bank of Canada
Ontario, Canada
$616M +$78.2M +175,700 +15%
Massachusetts Financial Services
33
Massachusetts Financial Services
Massachusetts
$572M -$330M -740,554 -37%
DZ Bank
34
DZ Bank
Germany
$537M +$109M +244,942 +25%
Amundi
35
Amundi
France
$518M -$898M -1,965,643 -63%
WCM Investment Management
36
WCM Investment Management
California
$514M +$28.6M +64,730 +6%
NL
37
Nuveen LLC
North Carolina
$473M +$28.4M +63,817 +6%
Renaissance Technologies
38
Renaissance Technologies
New York
$447M -$74.2M -166,683 -14%
Barclays
39
Barclays
United Kingdom
$366M -$1.33M -2,993 -0.4%
Swiss National Bank
40
Swiss National Bank
Switzerland
$346M +$23.2M +52,100 +7%
Pictet Asset Management
41
Pictet Asset Management
Switzerland
$327M +$33.2M +74,635 +11%
California Public Employees Retirement System
42
California Public Employees Retirement System
California
$323M -$37.5M -84,179 -10%
HL
43
Harding Loevner
New Jersey
$317M +$5.86M +13,152 +2%
Wells Fargo
44
Wells Fargo
California
$313M -$1.83M -4,117 -0.6%
UBS Group
45
UBS Group
Switzerland
$312M -$16.7M -37,416 -5%
VOYA Investment Management
46
VOYA Investment Management
Georgia
$311M -$56.7M -127,494 -15%
Sumitomo Mitsui Trust Group
47
Sumitomo Mitsui Trust Group
Japan
$292M +$4.93M +11,063 +2%
Artisan Partners
48
Artisan Partners
Wisconsin
$289M -$30.7M -68,872 -10%
HSBC Holdings
49
HSBC Holdings
United Kingdom
$286M -$90.2M -202,714 -24%
Citigroup
50
Citigroup
New York
$267M -$12.7M -28,636 -5%
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