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Vertex Pharmaceuticals

1,033 hedge funds and large institutions have $50.2B invested in Vertex Pharmaceuticals in 2021 Q4 according to their latest regulatory filings, with 201 funds opening new positions, 336 increasing their positions, 368 reducing their positions, and 87 closing their positions.

New
Increased
Maintained
Reduced
Closed

131% more first-time investments, than exits

New positions opened: 201 | Existing positions closed: 87

50% more funds holding in top 10

Funds holding in top 10: 69 (+3)

23% more call options, than puts

Call options by funds: $673M | Put options by funds: $547M

20% more capital invested

Capital invested by funds: $41.8B → $50.2B (+$8.37B)

11% more funds holding

Funds holding: 9331,033 (+100)

1.32% more ownership

Funds ownership: 89.26%90.57% (+1.3%)

9% less repeat investments, than reductions

Existing positions increased: 336 | Existing positions reduced: 368

Holders
1,033
Holders Change
+100
Holders Change %
+10.72%
% of All Funds
15.9%
Holding in Top 10
9
Holding in Top 10 Change
+3
Holding in Top 10 Change %
+50%
% of All Funds
0.14%
New
201
Increased
336
Reduced
368
Closed
87
Calls
$673M
Puts
$547M
Net Calls
+$126M
Net Calls Change
+$151M
Name Holding Trade Value Shares
Change
Change in
Stake
BG
26
Bellevue Group
Switzerland
$393M +$5.86M +30,145 +2%
Canada Pension Plan Investment Board
27
Canada Pension Plan Investment Board
Ontario, Canada
$375M +$3.03M +15,560 +0.9%
Renaissance Technologies
28
Renaissance Technologies
New York
$357M -$51.5M -264,618 -14%
N
29
Nuveen
North Carolina
$295M -$4.16M -21,391 -2%
Charles Schwab
30
Charles Schwab
California
$277M +$3.83M +19,703 +2%
Caisse de Depot et Placement du Quebec (CDPQ)
31
Caisse de Depot et Placement du Quebec (CDPQ)
Quebec, Canada
$270M -$51.9M -266,708 -18%
PAMS
32
Pictet Asset Management (Switzerland)
Switzerland
$266M +$28.7M +147,497 +14%
Goldman Sachs
33
Goldman Sachs
New York
$261M -$40.1M -206,385 -15%
Invesco
34
Invesco
Georgia
$246M -$18M -92,335 -8%
APG Asset Management
35
APG Asset Management
Netherlands
$233M -$4.3M -22,100 -2%
Franklin Resources
36
Franklin Resources
California
$233M +$37.4M +192,377 +22%
Sumitomo Mitsui Trust Group
37
Sumitomo Mitsui Trust Group
Japan
$228M -$10.2M -52,295 -5%
Impax Asset Management Group
38
Impax Asset Management Group
United Kingdom
$227M -$8.14M -41,881 -4%
D.E. Shaw & Co
39
D.E. Shaw & Co
New York
$224M -$135M -693,311 -40%
Swiss National Bank
40
Swiss National Bank
Switzerland
$217M -$7.31M -37,600 -4%
Morgan Stanley
41
Morgan Stanley
New York
$213M -$14.1M -72,706 -7%
Man Group
42
Man Group
United Kingdom
$212M -$48.2M -247,918 -20%
Dimensional Fund Advisors
43
Dimensional Fund Advisors
Texas
$205M +$44.6M +229,487 +33%
AIM
44
ARK Investment Management
Florida
$204M -$152M -780,960 -46%
VNIM
45
Vaughan Nelson Investment Management
Texas
$203M +$180M +923,747 New
Lazard Asset Management
46
Lazard Asset Management
New York
$201M +$146M +749,784 +452%
PPA
47
Parametric Portfolio Associates
Washington
$193M +$27.6M +142,022 +19%
MNG
48
Manning & Napier Group
New York
$192M +$203K +1,044 +0.1%
Amundi
49
Amundi
France
$187M +$26M +133,856 +19%
Wells Fargo
50
Wells Fargo
California
$186M -$55.6M -285,787 -25%

VRTX Hedge Fund Activity: Q4 2021 in Review

1,033 of the 6,498 institutional investors tracked by Wall St. Rank reported a position in Vertex Pharmaceuticals (VRTX) for Q4 2021, worth a combined $50.2B — up 20% from $41.8B a quarter earlier.

Buyers outnumbered sellers: 201 funds opened new VRTX positions and 87 closed out — a net gain of 114 holders — while 336 added to existing stakes and 368 trimmed.

The largest buyer was Fidelity Investments, adding an estimated $820M. The largest seller was Capital International Investors, cutting an estimated $374M.

  • 1,033 institutional investors held Vertex Pharmaceuticals (VRTX) as of Q4 2021, up from 933 in Q3 2021.
  • Funds reported $50.2B of Vertex Pharmaceuticals stock for Q4 2021, up 20% quarter-over-quarter.
  • 201 funds opened new Vertex Pharmaceuticals positions in Q4 2021 and 87 closed out, a net change of +114 holders.
  • The largest Vertex Pharmaceuticals buyer in Q4 2021 was Fidelity Investments, an estimated $820M added.
  • The largest Vertex Pharmaceuticals seller in Q4 2021 was Capital International Investors, an estimated $374M sold.

Based on aggregated 13F filings for Q4 2021.