|
1
|
Frazier Management
Seattle,
Washington
|
$33.5M
|
–
|
–
|
–
|
|
|
2
|
Novo Holdings A/S
Hellerup,
Denmark
|
$25.5M
|
-$2.37M
|
-254,314
|
-11%
|
|
|
3
|
Fidelity Investments
Boston,
Massachusetts
|
$16.3M
|
-$1.25M
|
-133,947
|
-9%
|
|
|
4
|
BVF Inc
San Francisco,
California
|
$15.7M
|
–
|
–
|
–
|
|
|
5
|
Franklin Resources
San Mateo,
California
|
$9.42M
|
+$1.52M
|
+163,600
|
+28%
|
|
|
6
|
Stonepine Capital Management
Bend,
Oregon
|
$8.01M
|
-$1.82M
|
-195,410
|
-23%
|
|
|
7
|
Abingworth
London,
United Kingdom
|
$7.38M
|
–
|
–
|
–
|
|
|
8
|
BB Biotech
Schaffhausen,
Switzerland
|
$5.88M
|
+$4.36M
|
+468,000
|
New
|
|
|
9
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.26M
|
+$178K
|
+19,125
|
+6%
|
|
|
10
|
|
$3.47M
|
+$2.57M
|
+276,440
|
New
|
|
|
11
|
BlackRock Fund Advisors
San Francisco,
California
|
$2.86M
|
+$1.53M
|
+163,943
|
+257%
|
|
|
12
|
Marshall Wace
London,
United Kingdom
|
$2.12M
|
-$256K
|
-27,447
|
-14%
|
|
|
13
|
EverPoint Asset Management
Stamford,
Connecticut
|
$1.88M
|
-$1.44M
|
-154,593
|
-51%
|
|
|
14
|
Northern Trust
Chicago,
Illinois
|
$1.47M
|
+$710K
|
+76,282
|
+187%
|
|
|
15
|
Millennium Management
New York
|
$1.42M
|
+$632K
|
+67,861
|
+149%
|
|
|
16
|
State Street
Boston,
Massachusetts
|
$1.38M
|
+$621K
|
+66,652
|
+155%
|
|
|
17
|
BlackRock Institutional Trust
San Francisco,
California
|
$960K
|
+$343K
|
+36,817
|
+93%
|
|
|
18
|
Nexthera Capital
New York
|
$942K
|
+$279K
|
+30,000
|
+67%
|
|
|
19
|
TFS Capital
West Chester,
Pennsylvania
|
$533K
|
+$395K
|
+42,404
|
New
|
|
|
20
|
Renaissance Technologies
New York
|
$468K
|
+$68K
|
+7,300
|
+24%
|
|
|
21
|
Geode Capital Management
Boston,
Massachusetts
|
$409K
|
+$3.82K
|
+410
|
+1%
|
|
|
22
|
BlackRock Investment Management
Wilmington,
Delaware
|
$405K
|
+$225K
|
+24,147
|
+299%
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$365K
|
+$211K
|
+22,652
|
+352%
|
|
|
24
|
Bank of New York Mellon
New York
|
$263K
|
+$195K
|
+20,894
|
New
|
|
|
25
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$255K
|
+$154K
|
+16,576
|
+431%
|
|
