|
1
|
Novo Holdings A/S
Hellerup,
Denmark
|
$26M
|
–
|
–
|
–
|
|
|
2
|
Fidelity Investments
Boston,
Massachusetts
|
$12.4M
|
+$18M
|
+1,279,588
|
New
|
|
|
3
|
BVF Inc
San Francisco,
California
|
$11.4M
|
–
|
–
|
–
|
|
|
4
|
Abingworth
London,
United Kingdom
|
$5.66M
|
–
|
–
|
–
|
|
|
5
|
EverPoint Asset Management
Stamford,
Connecticut
|
$3.28M
|
+$4.77M
|
+340,000
|
New
|
|
|
6
|
Vanguard Group
Malvern,
Pennsylvania
|
$2.97M
|
+$645K
|
+45,942
|
+18%
|
|
|
7
|
Sabby Management
Miami Beach,
Florida
|
$1.69M
|
+$2.46M
|
+174,943
|
New
|
|
|
8
|
Sphera Funds Management
Tel Aviv,
Israel
|
$1.33M
|
–
|
–
|
–
|
|
|
9
|
|
$1.03M
|
+$846K
|
+60,284
|
+130%
|
|
|
10
|
Polar Capital
London,
United Kingdom
|
$653K
|
+$470K
|
+33,510
|
+98%
|
|
|
11
|
BlackRock Fund Advisors
San Francisco,
California
|
$634K
|
+$136K
|
+9,694
|
+17%
|
|
|
12
|
DAFNA Capital Management
Los Angeles,
California
|
$436K
|
+$633K
|
+45,092
|
New
|
|
|
13
|
BlackRock Institutional Trust
San Francisco,
California
|
$386K
|
+$368K
|
+26,250
|
+191%
|
|
|
14
|
Millennium Management
New York
|
$385K
|
+$66.5K
|
+4,740
|
+14%
|
|
|
15
|
Renaissance Technologies
New York
|
$358K
|
+$164K
|
+11,700
|
+46%
|
|
|
16
|
|
$278K
|
-$423K
|
-30,110
|
-51%
|
|
|
17
|
TFS Capital
West Chester,
Pennsylvania
|
$256K
|
+$38.9K
|
+2,770
|
+12%
|
|
|
18
|
Geode Capital Management
Boston,
Massachusetts
|
$249K
|
+$363K
|
+25,836
|
New
|
|
|
19
|
Canaan Partners VII
Westport,
Connecticut
|
$230K
|
-$8.23M
|
-586,628
|
-96%
|
|
|
20
|
Northern Trust
Chicago,
Illinois
|
$202K
|
+$41.5K
|
+2,960
|
+16%
|
|
|
21
|
William Blair & Company
Chicago,
Illinois
|
$174K
|
–
|
–
|
–
|
|
|
22
|
State Street
Boston,
Massachusetts
|
$150K
|
-$134K
|
-9,536
|
-38%
|
|
|
23
|
Eidelman Virant Capital
Saint Louis,
Missouri
|
$145K
|
+$70.2K
|
+5,000
|
+50%
|
|
|
24
|
|
$124K
|
-$13.4K
|
-956
|
-7%
|
|
|
25
|
BlackRock Advisors
Wilmington,
Delaware
|
$94K
|
+$120K
|
+8,517
|
+687%
|
|
