|
1
|
Novo Holdings A/S
Hellerup,
Denmark
|
$46.5M
|
+$39.4M
|
+2,696,405
|
New
|
|
|
2
|
BVF Inc
San Francisco,
California
|
$20.3M
|
+$14.1M
|
+966,064
|
+462%
|
|
|
3
|
Canaan Partners VII
Westport,
Connecticut
|
$10.5M
|
+$8.93M
|
+610,434
|
New
|
|
|
4
|
Abingworth
London,
United Kingdom
|
$10.2M
|
+$8.62M
|
+589,244
|
New
|
|
|
5
|
Vanguard Group
Malvern,
Pennsylvania
|
$4.51M
|
+$2.9M
|
+198,487
|
+315%
|
|
|
6
|
Sphera Funds Management
Tel Aviv,
Israel
|
$2.37M
|
+$2.01M
|
+137,622
|
New
|
|
|
7
|
|
$1.02M
|
+$833K
|
+56,979
|
+3,004%
|
|
|
8
|
BlackRock Fund Advisors
San Francisco,
California
|
$965K
|
+$134K
|
+9,159
|
+20%
|
|
|
9
|
|
$799K
|
+$675K
|
+46,185
|
+34,989%
|
|
|
10
|
Millennium Management
New York
|
$605K
|
+$513K
|
+35,091
|
New
|
|
|
11
|
Polar Capital
London,
United Kingdom
|
$588K
|
+$132K
|
+9,060
|
+36%
|
|
|
12
|
Deutsche Bank
Frankfurt Am Main Ge,
Germany
|
$501K
|
+$2.06K
|
+141
|
+0.5%
|
|
|
13
|
Renaissance Technologies
New York
|
$438K
|
+$271K
|
+18,520
|
+271%
|
|
|
14
|
State Street
Boston,
Massachusetts
|
$435K
|
+$231K
|
+15,807
|
+169%
|
|
|
15
|
Paloma Partners
Greenwich,
Connecticut
|
$435K
|
+$369K
|
+25,224
|
New
|
|
|
16
|
TFS Capital
West Chester,
Pennsylvania
|
$409K
|
+$346K
|
+23,685
|
New
|
|
|
17
|
William Blair & Company
Chicago,
Illinois
|
$312K
|
+$265K
|
+18,100
|
New
|
|
|
18
|
Northern Trust
Chicago,
Illinois
|
$310K
|
-$6.74K
|
-461
|
-2%
|
|
|
19
|
|
$238K
|
+$202K
|
+13,816
|
New
|
|
|
20
|
BlackRock Institutional Trust
San Francisco,
California
|
$237K
|
+$1.11K
|
+76
|
+0.6%
|
|
|
21
|
Eidelman Virant Capital
Saint Louis,
Missouri
|
$173K
|
+$146K
|
+10,000
|
New
|
|
|
22
|
BlackRock Investment Management
Wilmington,
Delaware
|
$135K
|
+$44.4K
|
+3,035
|
+64%
|
|
|
23
|
TIAA CREF Investment Management
New York
|
$111K
|
-$17.4K
|
-1,188
|
-16%
|
|
|
24
|
California State Teachers Retirement System (CalSTRS)
West Sacramento,
California
|
$76K
|
+$18K
|
+1,231
|
+39%
|
|
|
25
|
US Bancorp
Minneapolis,
Minnesota
|
$76K
|
+$64.3K
|
+4,400
|
New
|
|
