Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
51 hedge funds and large institutions have $26M invested in Synlogic in 2022 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 14 increasing their positions, 9 reducing their positions, and 8 closing their positions.
56% more repeat investments, than reductions
Existing positions increased: 14 | Existing positions reduced: 9
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
0.55% less ownership
Funds ownership: 3.78% → 3.23% (-0.55%)
4% less funds holding
Funds holding: 53 → 51 (-2)
13% less first-time investments, than exits
New positions opened: 7 | Existing positions closed: 8
31% less capital invested
Capital invested by funds: $37.8M → $26M (-$11.9M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
UOC
UBS O'Connor
Chicago,
Illinois
|
+$138K |
| 2 |
Millennium Management
New York
|
+$59.7K |
| 3 |
Envestnet Asset Management
Chicago,
Illinois
|
+$46.9K |
| 4 |
PAM
PVG Asset Management
Golden,
Colorado
|
+$41.8K |
| 5 |
Fidelity Investments
Boston,
Massachusetts
|
+$35.5K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$4.39M |
| 2 |
Alyeska Investment Group
Chicago,
Illinois
|
-$807K |
| 3 |
Renaissance Technologies
New York
|
-$15.6K |
| 4 |
Citadel Advisors
Miami,
Florida
|
-$14K |
| 5 |
FHA
Flagship Harbor Advisors
Boston,
Massachusetts
|
-$13K |
SYBX Hedge Fund Activity: Q4 2022 in Review
51 of the 6,237 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q4 2022, worth a combined $26M — down 31% from $37.8M a quarter earlier.
Sellers outnumbered buyers: 8 funds closed out of SYBX and 7 opened new positions — a net loss of 1 holder — while 9 trimmed existing stakes and 14 added.
The largest buyer was UBS O'Connor, adding an estimated $138K. The largest seller was RA Capital Management, exiting entirely with an estimated $4.39M sold.
- 51 institutional investors held Synlogic (SYBX) as of Q4 2022, down from 53 in Q3 2022.
- Funds reported $26M of Synlogic stock for Q4 2022, down 31% quarter-over-quarter.
- 7 funds opened new Synlogic positions in Q4 2022 and 8 closed out, a net change of -1 holder.
- The largest Synlogic buyer in Q4 2022 was UBS O'Connor, an estimated $138K added.
- The largest Synlogic seller in Q4 2022 was RA Capital Management, an estimated $4.39M sold.
Based on aggregated 13F filings for Q4 2022.