Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
51 hedge funds and large institutions have $46.9M invested in Synlogic in 2022 Q2 according to their latest regulatory filings, with 4 funds opening new positions, 15 increasing their positions, 16 reducing their positions, and 6 closing their positions.
400% more call options, than puts
Call options by funds: $5K | Put options by funds: $1K
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
0.22% less ownership
Funds ownership: 4.09% → 3.87% (-0.22%)
6% less repeat investments, than reductions
Existing positions increased: 15 | Existing positions reduced: 16
4% less funds holding
Funds holding: 53 → 51 (-2)
33% less first-time investments, than exits
New positions opened: 4 | Existing positions closed: 6
55% less capital invested
Capital invested by funds: $103M → $46.9M (-$56.4M)
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Alyeska Investment Group
Chicago,
Illinois
|
+$875K |
| 2 |
UOC
UBS O'Connor
Chicago,
Illinois
|
+$256K |
| 3 |
Millennium Management
New York
|
+$68K |
| 4 |
State Street
Boston,
Massachusetts
|
+$38.2K |
| 5 |
BlackRock
New York
|
+$36.8K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
OM
Opaleye Management
Boston,
Massachusetts
|
-$2.36M |
| 2 |
SCM
Stonepine Capital Management
Bend,
Oregon
|
-$1.4M |
| 3 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$1.21M |
| 4 |
Susquehanna International Group
Bala Cynwyd,
Pennsylvania
|
-$221K |
| 5 |
UBS Group
Zurich,
Switzerland
|
-$84K |
SYBX Hedge Fund Activity: Q2 2022 in Review
51 of the 5,959 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q2 2022, worth a combined $46.9M — down 55% from $103M a quarter earlier.
Sellers outnumbered buyers: 6 funds closed out of SYBX and 4 opened new positions — a net loss of 2 holders — while 16 trimmed existing stakes and 15 added.
The largest buyer was Alyeska Investment Group, adding an estimated $875K. The largest seller was Opaleye Management, exiting entirely with an estimated $2.36M sold.
- 51 institutional investors held Synlogic (SYBX) as of Q2 2022, down from 53 in Q1 2022.
- Funds reported $46.9M of Synlogic stock for Q2 2022, down 55% quarter-over-quarter.
- 4 funds opened new Synlogic positions in Q2 2022 and 6 closed out, a net change of -2 holders.
- The largest Synlogic buyer in Q2 2022 was Alyeska Investment Group, an estimated $875K added.
- The largest Synlogic seller in Q2 2022 was Opaleye Management, an estimated $2.36M sold.
Based on aggregated 13F filings for Q2 2022.