Synlogic
SYBX
SYBX was delisted on the 20th of January, 2026.
51 hedge funds and large institutions have $25.5M invested in Synlogic in 2022 Q4 according to their latest regulatory filings, with 7 funds opening new positions, 13 increasing their positions, 9 reducing their positions, and 9 closing their positions.
44% more repeat investments, than reductions
Existing positions increased: 13 | Existing positions reduced: 9
0% more funds holding in top 10
Funds holding in top 10: 2 → 2 (0)
0.57% less ownership
Funds ownership: 3.78% → 3.21% (-0.57%)
4% less funds holding
Funds holding: 53 → 51 (-2)
21% less capital invested
Capital invested by funds: $32.1M → $25.5M (-$6.61M)
22% less first-time investments, than exits
New positions opened: 7 | Existing positions closed: 9
Top Buyers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
Millennium Management
New York
|
+$59.7K |
| 2 |
Envestnet Asset Management
Chicago,
Illinois
|
+$46.9K |
| 3 |
PAM
PVG Asset Management
Golden,
Colorado
|
+$41.8K |
| 4 |
Fidelity Investments
Boston,
Massachusetts
|
+$35.5K |
| 5 |
Prudential Financial
Newark,
New Jersey
|
+$24.6K |
Top Sellers
| Rank | Fund | Capital Flow |
|---|---|---|
| 1 |
RCM
RA Capital Management
Boston,
Massachusetts
|
-$4.39M |
| 2 |
Alyeska Investment Group
Chicago,
Illinois
|
-$807K |
| 3 |
UOC
UBS O'Connor
Chicago,
Illinois
|
-$442K |
| 4 |
Renaissance Technologies
New York
|
-$15.6K |
| 5 |
Citadel Advisors
Miami,
Florida
|
-$14K |
| Name | Holding | Trade Value |
Shares Change |
Change in Stake |
|
|---|---|---|---|---|---|
|
UOC
51
UBS O'Connor
Chicago,
Illinois
| – | -$442K | -31,049 | Closed |
|
|
52
Citadel Advisors
Miami,
Florida
| – | -$14K | -1,000 | Closed |
|
|
HF
53
HRT Financial
New York
| – | -$12K | -880 | Closed |
|
|
TF
54
TIAA FSB
Jacksonville,
Florida
| – | -$12K | -817 | Closed |
|
55
Connor, Clark & Lunn Investment Management (CC&L)
Vancouver,
British Columbia, Canada
| – | -$11K | -780 | Closed |
|
|
PP
56
PFS Partners
Mine Hill,
New Jersey
| – | -$1.9K | -133 | Closed |
|
|
AIM
57
Axiom Investment Management
New York
| – | -$1K | -100 | Closed |
|
|
HBW
58
Hazlett, Burt & Watson
Wheeling,
West Virginia
| – | -$1K | -100 | Closed |
|
59
Simplex Trading
Chicago,
Illinois
| – | -$207 | -17 | -65% |
|
60
JP Morgan Chase
New York
| – | +$366 | +30 | +3,000% |
|
SYBX Hedge Fund Activity: Q4 2022 in Review
51 of the 6,221 institutional investors tracked by Wall St. Rank reported a position in Synlogic (SYBX) for Q4 2022, worth a combined $25.5M — down 21% from $32.1M a quarter earlier.
Sellers outnumbered buyers: 9 funds closed out of SYBX and 7 opened new positions — a net loss of 2 holders — while 9 trimmed existing stakes and 13 added.
The largest buyer was Millennium Management, adding an estimated $59.7K. The largest seller was RA Capital Management, exiting entirely with an estimated $4.39M sold.
- 51 institutional investors held Synlogic (SYBX) as of Q4 2022, down from 53 in Q3 2022.
- Funds reported $25.5M of Synlogic stock for Q4 2022, down 21% quarter-over-quarter.
- 7 funds opened new Synlogic positions in Q4 2022 and 9 closed out, a net change of -2 holders.
- The largest Synlogic buyer in Q4 2022 was Millennium Management, an estimated $59.7K added.
- The largest Synlogic seller in Q4 2022 was RA Capital Management, an estimated $4.39M sold.
Based on aggregated 13F filings for Q4 2022.